MEK1 抗体 (AA 289-293)
Quick Overview for MEK1 抗体 (AA 289-293) (ABIN362998)
抗原
See all MEK1 (MAP2K1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 289-293
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特异性
- The antibody detects endogenous level of total MEK1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Peptide sequence around AA 289-293 (P-R-T-P-G) derived from Human MEK1. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
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亚型
- IgG
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应用备注
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Western blotting: 1:500-1:1000
Immunohistochemistry: 1:50-1:100 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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: "CD40-expressing plasmid induces anti-CD40 antibody and enhances immune responses to DNA vaccination." in: The journal of gene medicine, Vol. 12, Issue 1, pp. 97-106, (2010) (PubMed).
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: "CD40-expressing plasmid induces anti-CD40 antibody and enhances immune responses to DNA vaccination." in: The journal of gene medicine, Vol. 12, Issue 1, pp. 97-106, (2010) (PubMed).
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- MEK1 (MAP2K1) (Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))
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别名
- MEK1
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背景
- Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates ERK1 and ERK2 MAP kinases.
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分子量
- 45 kDa
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NCBI登录号
- NP_002746
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UniProt
- Q02750
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途径
- MAPK Pathway, RTK signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling
抗原
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