c-MET 抗体 (AA 1232-1236)
Quick Overview for c-MET 抗体 (AA 1232-1236) (ABIN362880)
抗原
See all c-MET (MET) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1232-1236
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特异性
- The antibody detects endogenous level of total Met protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.
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免疫原
- Peptide sequence around AA 1232-1236 (K-E-Y-Y-S) derived from Human Met. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
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亚型
- IgG
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应用备注
- Western blotting: 1:500-1:1000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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: "MicroRNA-449a is downregulated in non-small cell lung cancer and inhibits migration and invasion by targeting c-Met." in: PLoS ONE, Vol. 8, Issue 5, pp. e64759, (2013) (PubMed).
: "miR-34a inhibits migration and invasion by down-regulation of c-Met expression in human hepatocellular carcinoma cells." in: Cancer letters, Vol. 275, Issue 1, pp. 44-53, (2009) (PubMed).
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: "MicroRNA-449a is downregulated in non-small cell lung cancer and inhibits migration and invasion by targeting c-Met." in: PLoS ONE, Vol. 8, Issue 5, pp. e64759, (2013) (PubMed).
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- c-MET (MET) (Met Proto-Oncogene (MET))
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别名
- Met
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背景
- Receptor for hepatocyte growth factor and scatter factor. Has a tyrosine-protein kinase activity. Functions in cell proliferation, scattering, morphogenesis and survival.
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分子量
- 156 kDa
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NCBI登录号
- NP_000236
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UniProt
- P08581
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途径
- RTK signaling, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor
抗原
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