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FLT1 抗体 (C-Term)

FLT1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN360966
发货至: 中国
  • 抗原 See all FLT1 抗体
    FLT1 (Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))
    抗原表位
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    C-Term
    适用
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    宿主
    • 134
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    克隆类型
    • 136
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    多克隆
    标记
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    This FLT1 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Immunofluorescence (IF)
    序列
    CNKKAVFSRI SKFKSTRNDS TTQSNVKH
    特异性
    This antibody recognizes the recombinant soluble VEGFR-1/FLT-1 (native) but not the recombinant soluble VEGFR-1/FLT-1 (D1-5) both produced in Insects cells. Because of the different glycosylation of insect cells compared to mammalian cells the MW of sFlt-1 (native) is about 96 kDa instead of about 110 kDa of the naturally occurring sFlt-1. The antibody did not cross react with recombinant Human soluble KDR (D1-7).
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Protein A Chromatography.
    免疫原
    Peptide of the C-terminal end of native Human soluble VEGFR-1/Flt-1
    亚型
    IgG
    Top Product
    Discover our top product FLT1 Primary Antibody
  • 应用备注
    Western Blot: This VEGFR1 antibody can be used at 0.5-2.0 μg/mL with the appropriatesecondary reagents to detect native Human sVEGFR-1/Flt-1. Immunofluorescence.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 溶解方式
    Restore in sterile water to a concentration of > 0.5 mg/mL
    缓冲液
    PBS, pH 7.2 without preservatives or stabilizers.
    储存液
    Without preservative
    注意事项
    This product is photosensitive and should be protected from light
    储存条件
    4 °C
    储存方法
    Prior to and following reconstitution store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
  • 抗原
    FLT1 (Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))
    别名
    VEGFR-1 / Flt-1 (FLT1 产品)
    别名
    FLT antibody, FLT-1 antibody, VEGFR-1 antibody, VEGFR1 antibody, FLT1 antibody, flt1b antibody, sFlt1 antibody, AI323757 antibody, Flt-1 antibody, fms related tyrosine kinase 1 antibody, FMS-related tyrosine kinase 1 antibody, vascular endothelial growth factor receptor 1 antibody, fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) antibody, FMS-like tyrosine kinase 1 antibody, vascular endothelial growth factor receptor-1 antibody, FLT1 antibody, Flt1 antibody, CpipJ_CPIJ012087 antibody, flt1 antibody, FLT-1 antibody
    背景
    Three cell membrane receptor tyrosine kinases, Flt (also designated VEGF-R1), Flk-1 (also designated VEGF-R2) and Flt-4, putatively involved in the growth of endothelial cells, are characterized by the presence of seven immunoglobulinlike sequences in their extracellular domain. These receptors exhibit high degrees of sequence relatedness to each other as well as lesser degrees of relatedness to the class III receptors, including CSF-1/Fms, PDGR, SLFR/Kit and Flt-3/Flk-2. Two members of this receptor class, Flt-1 and Flk-1, have been shown to represent high affinity receptors for vascular endothelial growth factors (VEGFs). On the basis of structural similarity to Flt and Flk-1, it has been speculated that Flt-4 might represent a third receptor for either VEGF or a VEGF-related ligand.Synonyms: FLT, FLT1, FRT, Fms-like tyrosine kinase 1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, VEGF Receptor 1, VEGFR1, Vascular endothelial growth factor receptor 1, Vascular permeability factor receptor
    基因ID
    2321
    NCBI登录号
    NP_001153392
    UniProt
    P17948
    途径
    RTK signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
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