PI4K2A 抗体 (N-Term)
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- 抗原 See all PI4K2A 抗体
- PI4K2A (Phosphatidylinositol 4-Kinase Type 2 alpha (PI4K2A))
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抗原表位
- N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PI4K2A antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 特异性
- This antibody reacts to PI4K2A.
- 纯化方法
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
- 免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human PI4K II.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product PI4K2A Primary Antibody
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anti-Phosphatidylinositol 4-Kinase Type 2 alpha (PI4K2A) (AA 1-479) antibody
PI4K2A 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidylinositol 4-Kinase Type 2 alpha (PI4K2A) (AA 1-30), (N-Term) antibodyPI4K2A 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB1679 unconjugated
anti-Phosphatidylinositol 4-Kinase Type 2 alpha (PI4K2A) (AA 1-479) antibodyPI4K2A 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Phosphatidylinositol 4-Kinase Type 2 alpha (PI4K2A) (AA 383-477) antibodyPI4K2A 适用: 人 ELISA 宿主: 小鼠 Monoclonal 3E1 unconjugated
anti-Phosphatidylinositol 4-Kinase Type 2 alpha (PI4K2A) (AA 131-479) antibodyPI4K2A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidylinositol 4-Kinase Type 2 alpha (PI4K2A) (AA 387-415), (C-Term) antibodyPI4K2A 适用: 人 WB 宿主: 兔 Polyclonal RB36306 unconjugated
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- 应用备注
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ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.25 mg/mL
- 缓冲液
- PBS with 0.09 % (W/V) sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- 抗原
- PI4K2A (Phosphatidylinositol 4-Kinase Type 2 alpha (PI4K2A))
- 别名
- PI4K2A (PI4K2A 产品)
- 别名
- pi4k2 antibody, pi4kii antibody, PI4KII antibody, PIK42A antibody, RP11-548K23.6 antibody, Pi4k2 antibody, Pi4KII antibody, pi4kII alpha antibody, wu:fc84f05 antibody, zgc:63646 antibody, phosphatidylinositol 4-kinase type 2 alpha antibody, phosphatidylinositol 4-kinase type 2 alpha L homeolog antibody, PI4K2A antibody, pi4k2a antibody, pi4k2a.L antibody, Pi4k2a antibody
- 背景
- Phosphatidylinositolpolyphosphates (PtdInsPs) are centrally involved in many biologic processes, ranging from cell growth and organization of the actin cytoskeleton to endo- and exocytosis. PI4KII phosphorylates PtdIns at the D-4 position, an essential step in the biosynthesis of PtdInsPs. PI4K II is activated by detergent and inhibited by adenosine. Overexpression of PI4KII in COS-7 cells increases synthesis of PtdIns4P. Some cells overexpressing PI4KII have scattered or no perinuclear Golgi. Knockdown of PI4KII by RNA interference (RNAi) does not disrupt the Golgi, and some cells show expanded Golgi. RNAi reduces the Golgi level of PtdIns4P and blocks the association between AP1 and the trans-Golgi network. PI4KII RNAi had little effect on intra-Golgi trafficking, but it inhibited export to plasma membrane export by 35 % . It has been proposed that PI4KII generates PtdIns4P-rich domains within the Golgi that specify docking of the AP1 coat machinery.Synonyms: Phosphatidylinositol 4-kinase type 2-alpha, Phosphatidylinositol 4-kinase type II-alpha
- 基因ID
- 55361, 9606
- UniProt
- Q9BTU6
- 途径
- Inositol Metabolic Process, Synaptic Membrane
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