PI4K2A 抗体 (N-Term)
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- 抗原 See all PI4K2A 抗体
- PI4K2A (Phosphatidylinositol 4-Kinase Type 2 alpha (PI4K2A))
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抗原表位
- AA 1-30, N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PI4K2A antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- This antibody is purified through a protein G column, followed by dialysis against PBS.
- 免疫原
- This PI4K2A (PI4K II) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human PI4K2A (PI4K II).
- 克隆位点
- RB1679
- 亚型
- Ig Fraction
- Top Product
- Discover our top product PI4K2A Primary Antibody
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anti-Phosphatidylinositol 4-Kinase Type 2 alpha (PI4K2A) (AA 1-479) antibody
PI4K2A 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidylinositol 4-Kinase Type 2 alpha (PI4K2A) (AA 1-479) antibodyPI4K2A 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Phosphatidylinositol 4-Kinase Type 2 alpha (PI4K2A) (AA 383-477) antibodyPI4K2A 适用: 人 ELISA 宿主: 小鼠 Monoclonal 3E1 unconjugated
anti-Phosphatidylinositol 4-Kinase Type 2 alpha (PI4K2A) (AA 131-479) antibodyPI4K2A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidylinositol 4-Kinase Type 2 alpha (PI4K2A) (AA 387-415), (C-Term) antibodyPI4K2A 适用: 人 WB 宿主: 兔 Polyclonal RB36306 unconjugated
anti-Phosphatidylinositol 4-Kinase Type 2 alpha (PI4K2A) (N-Term) antibodyPI4K2A 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- IF: 1:10~50. WB: 1:8000. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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- 抗原
- PI4K2A (Phosphatidylinositol 4-Kinase Type 2 alpha (PI4K2A))
- 别名
- PI4K2A (PI4K II) (PI4K2A 产品)
- 别名
- pi4k2 antibody, pi4kii antibody, PI4KII antibody, PIK42A antibody, RP11-548K23.6 antibody, Pi4k2 antibody, Pi4KII antibody, pi4kII alpha antibody, wu:fc84f05 antibody, zgc:63646 antibody, phosphatidylinositol 4-kinase type 2 alpha antibody, phosphatidylinositol 4-kinase type 2 alpha L homeolog antibody, PI4K2A antibody, pi4k2a antibody, pi4k2a.L antibody, Pi4k2a antibody
- 背景
- Phosphatidylinositolpolyphosphates (PtdInsPs) are centrally involved in many biologic processes, ranging from cell growth and organization of the actin cytoskeleton to endo- and exocytosis. PI4KII phosphorylates PtdIns at the D-4 position, an essential step in the biosynthesis of PtdInsPs. PI4K II is activated by detergent and inhibited by adenosine. Overexpression of PI4KII in COS-7 cells increases synthesis of PtdIns4P. Some cells overexpressing PI4KII have scattered or no perinuclear Golgi. Knockdown of PI4KII by RNA interference (RNAi) does not disrupt the Golgi, and some cells show expanded Golgi. RNAi reduces the Golgi level of PtdIns4P and blocks the association between AP1 and the trans-Golgi network. PI4KII RNAi had little effect on intra-Golgi trafficking, but it inhibited export to plasma membrane export by 35 % . It has been proposed that PI4KII generates PtdIns4P-rich domains within the Golgi that specify docking of the AP1 coat machinery.
- 分子量
- 54022
- 基因ID
- 55361
- NCBI登录号
- NP_060895
- UniProt
- Q9BTU6
- 途径
- Inositol Metabolic Process, Synaptic Membrane
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