MAP3K1 抗体 (C-Term)
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Quick Overview for MAP3K1 抗体 (C-Term) (ABIN360286)
抗原
See all MAP3K1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody reacts to MEKK1.
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纯化方法
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
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免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human MEKK1.
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亚型
- Ig Fraction
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anti-Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1) (AA 1307-1509) antibody
MAP3K1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1) (C-Term) antibodyMAP3K1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1) (pThr1402) antibodyMAP3K1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1) (AA 1211-1310) antibodyMAP3K1 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 2F6 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1) (AA 1077-1176) antibodyMAP3K1 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal 2F6 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1) (pThr1402) antibodyMAP3K1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1) (C-Term) antibodyMAP3K1 适用: 人, 小鼠, 大鼠, 兔, Cow, 豚鼠, 马, 斑马鱼, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1) (AA 1211-1310) antibodyMAP3K1 适用: 人 WB, IHC (p), IF, FACS 宿主: 小鼠 Monoclonal 2F6 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1) (pThr1402) antibodyMAP3K1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1) (AA 1251-1300) antibodyMAP3K1 适用: 人, 小鼠, 大鼠, 猴, 兔, Pig, Cow, 豚鼠, 马, 犬, Bat, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- MAP3K1 (Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1))
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别名
- MAP3K1
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背景
- Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MEKK1 can phosphorylate and activate MAPKK 1 and MAPKK 2 (MEK1/MEK2) which leads to phosphorylation of MAP kinases. It is also a highly efficient activator of the JNK cascade. The protein contains a putative 1 RING-type zinc finger and 1 SWIM-type zinc finger.Synonyms: MAPK/ERK kinase kinase 1, MAPKKK1, MEKK, MEKK1, Mitogen-activated protein kinase kinase kinase 1
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基因ID
- 4214, 9606
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UniProt
- Q13233
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途径
- MAPK Pathway, Interferon-gamma Pathway, Caspase Cascade in Apoptosis, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Regulation of Actin Filament Polymerization, Toll-Like Receptors Cascades
抗原
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