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Activin A Receptor Type IB/ALK-4 抗体 (Middle Region)

ACVR1B 适用: 人, 小鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN360114
发货至: 中国
  • 抗原 See all Activin A Receptor Type IB/ALK-4 (ACVR1B) 抗体
    Activin A Receptor Type IB/ALK-4 (ACVR1B) (Activin A Receptor, Type IB (ACVR1B))
    抗原表位
    • 15
    • 9
    • 7
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
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    Middle Region
    适用
    • 49
    • 39
    • 28
    • 1
    人, 小鼠
    宿主
    • 59
    • 13
    • 3
    • 2
    克隆类型
    • 62
    • 15
    多克隆
    标记
    • 35
    • 12
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Activin A Receptor Type IB/ALK-4 antibody is un-conjugated
    应用范围
    • 50
    • 36
    • 13
    • 13
    • 13
    • 10
    • 9
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody reacts to Activin A Receptor Type IB (ACVR1B).
    纯化方法
    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
    免疫原
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human ACVR1B.
    亚型
    Ig Fraction
    Top Product
    Discover our top product ACVR1B Primary Antibody
  • 应用备注
    ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Flow cytometry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS with 0.09 % (W/V) sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    Activin A Receptor Type IB/ALK-4 (ACVR1B) (Activin A Receptor, Type IB (ACVR1B))
    别名
    Activin Receptor Type 1B (ACVR1B) (ACVR1B 产品)
    别名
    ACVR1B antibody, alk4 antibody, skr2 antibody, alk-4 antibody, xalk4 antibody, actrib antibody, acvrlk4 antibody, DKFZp469A1614 antibody, 6820432J04 antibody, ActR-IB antibody, ActRIB antibody, Acvrlk4 antibody, Alk4 antibody, SKR2 antibody, ACTRIB antibody, ACVRLK4 antibody, ALK4 antibody, Skr2 antibody, axis antibody, taram-a antibody, tarama antibody, wu:fb75f01 antibody, activin A receptor type 1B antibody, Activin receptor type-1B antibody, activin A receptor, type IB antibody, activin A receptor, type 1B antibody, activin A receptor type 1Ba antibody, ACVR1B antibody, acvr1b antibody, acv1b antibody, Acvr1b antibody, acvr1ba antibody
    背景
    Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with a cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. The gene for ACVR1B (activin A type IB receptor) is composed of 11 exons. Alternative splicing and alternative polyadenylation result in 3 fully described transcript variants. The mRNA expression of variants 1, 2, and 3 is confirmed, and a potential fourth variant contains an alternative exon 8 and lacks exons 9 through 11, but its mRNA expression has not been confirmed.Synonyms: ACTR-IB, ACVRLK4, ALK4, Activin receptor type IB, Activin receptor-like kinase 4, SKR2, Serine/threonine-protein kinase receptor R2
    基因ID
    91, 9606
    UniProt
    P36896
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