FGFR3 抗体 (C-Term)
Quick Overview for FGFR3 抗体 (C-Term) (ABIN359858)
抗原
See all FGFR3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody reacts to FGFR3.
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纯化方法
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
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免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human FGFR3.
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亚型
- Ig Fraction
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anti-Fibroblast Growth Factor Receptor 3 (FGFR3) (AA 529-694) antibody
FGFR3 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 2H10B4 unconjugated
anti-Fibroblast Growth Factor Receptor 3 (FGFR3) (AA 166-375) antibodyFGFR3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor 3 (FGFR3) (AA 39-138) antibodyFGFR3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor 3 (FGFR3) (AA 23-375) antibodyFGFR3 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor 3 (FGFR3) (C-Term) antibodyFGFR3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor 3 (FGFR3) (AA 529-694) antibodyFGFR3 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1E3F9 unconjugated
anti-Fibroblast Growth Factor Receptor 3 (FGFR3) antibodyFGFR3 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Fibroblast Growth Factor Receptor 3 (FGFR3) (AA 131-180) antibodyFGFR3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor 3 (FGFR3) (AA 776-806) antibodyFGFR3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor 3 (FGFR3) (AA 468-495) antibodyFGFR3 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- FGFR3 (Fibroblast Growth Factor Receptor 3 (FGFR3))
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别名
- CD333 / FGFR3
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背景
- FGFR3 is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia.Synonyms: FGFR-3, Fibroblast growth factor receptor 3, JTK4
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基因ID
- 2261, 9606
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UniProt
- P22607
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Growth Factor Binding
抗原
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