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PAK1 抗体 (pThr212)

PAK1 适用: 人 EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN358296
发货至: 中国
  • 抗原 See all PAK1 抗体
    PAK1 (P21-Activated Kinase 1 (PAK1))
    抗原表位
    • 33
    • 17
    • 15
    • 13
    • 10
    • 10
    • 8
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    • 4
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    • 2
    • 2
    • 2
    • 1
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    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
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    • 1
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    pThr212
    适用
    • 172
    • 95
    • 83
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    宿主
    • 165
    • 4
    • 1
    • 1
    克隆类型
    • 160
    • 12
    多克隆
    标记
    • 89
    • 10
    • 7
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 4
    • 4
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    • 3
    This PAK1 antibody is un-conjugated
    应用范围
    • 116
    • 66
    • 45
    • 39
    • 39
    • 33
    • 31
    • 13
    • 11
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    • 6
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    Enzyme Immunoassay (EIA)
    特异性
    This antibody detects PAK1 pThr212. Predicted to cross react with Mouse (100 % Antigen Homology).
    纯化方法
    Protein A Affinity Chromatography. Then, the antibody fraction is peptide affinity purified in a 2-step procedure with peptides. The antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
    免疫原
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Thr212 of human PAK1.
    亚型
    Ig Fraction
    Top Product
    Discover our top product PAK1 Primary Antibody
  • 应用备注
    ELISA: 1/1,000. Dot Blot: 1/100-1/500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS with 0.09 % (W/V) Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    PAK1 (P21-Activated Kinase 1 (PAK1))
    别名
    PAK1 (PAK1 产品)
    别名
    X-PAK1 antibody, XPak1 antibody, pak antibody, pak-1 antibody, pakalpha antibody, PAKalpha antibody, AW045634 antibody, PAK-1 antibody, Paka antibody, p21 protein (Cdc42/Rac)-activated kinase 1 S homeolog antibody, p21 (RAC1) activated kinase 1 antibody, p21 protein (Cdc42/Rac)-activated kinase 1 antibody, Serine/threonine-protein kinase pak-1 antibody, pak1.S antibody, PAK1 antibody, Pak1 antibody, pak-1 antibody
    背景
    PAK proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. These proteins serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK1 regulates cell motility and morphology.Synonyms: Alpha-PAK, PAK 1, PAK alpha, PAK-1, Serine/threonine-protein kinase PAK 1, p21-activated kinase 1, p65-PAK
    分子量
    60516 Da
    基因ID
    5058, 9606
    UniProt
    Q13153
    途径
    MAPK Pathway, RTK signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Embryonic Body Morphogenesis
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