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Retinoblastoma 1 抗体 (pSer608)

This anti-Retinoblastoma 1 antibody is a 兔 多克隆 antibody detecting Retinoblastoma 1 in IHC (p) 和 EIA. Suitable for 人.
产品编号 ABIN358211
发货至: 中国

Quick Overview for Retinoblastoma 1 抗体 (pSer608) (ABIN358211)

抗原

See all Retinoblastoma 1 (RB1) 抗体
Retinoblastoma 1 (RB1)

适用

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宿主

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克隆类型

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多克隆

标记

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This Retinoblastoma 1 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
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    pSer608

    特异性

    This antibody detects Rb pSer608.

    纯化方法

    Protein G Affinity Chromatography. Then, the antibody fraction is peptide affinity purified in a 2-step procedure with control and phosphorylated peptides. The phospho-specific antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

    免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S608 of human RB.

    亚型

    Ig Fraction
  • 应用备注

    ELISA: 1/1,000. Dot Blot: 1/500. Immunohistochemistry: 1/50approx. 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    Retinoblastoma 1 (RB1)

    别名

    Retinoblastoma-Associated Protein / RB1

    背景

    Retinoblastoma (RB) is an embryonic malignant neoplasm of retinal origin. It almost always presents in early childhood and is often bilateral. Spontaneous regression ('cure') occurs in some cases.Synonyms: OSRC, Rb, Retinoblastoma 1, p105-Rb, pRb, pp110

    分子量

    106159 Da.

    基因ID

    5925, 9606

    UniProt

    P06400

    途径

    Cell Division Cycle, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Maintenance of Protein Location, Synthesis of DNA, Autophagy
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