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FGFR1 抗体 (pTyr766)

This anti-FGFR1 antibody is a 兔 多克隆 antibody detecting FGFR1 in WB, IHC (p) 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN358128
发货至: 中国

Quick Overview for FGFR1 抗体 (pTyr766) (ABIN358128)

抗原

See all FGFR1 抗体
FGFR1 (Fibroblast Growth Factor Receptor 1 (FGFR1))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This FGFR1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
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    pTyr766

    特异性

    This antibody detects FGFR pTyr766.

    纯化方法

    Protein G Affinity Chromatography. Then, the antibody fraction is peptide affinity purified in a 2-step procedure with control and phosphorylated peptides. The phospho-specific antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

    免疫原

    KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Tyr766 of Human FGFR. Genename: FGFR1

    亚型

    Ig Fraction
  • 应用备注

    ELISA: 1/1,000. Dot Blot: 1/500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    FGFR1 (Fibroblast Growth Factor Receptor 1 (FGFR1))

    别名

    FGFR1

    背景

    FGFR is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene can lead to Pfeiffer syndrome and Jackson-Weiss syndrome.Synonyms: BFGFR, Basic fibroblast growth factor receptor 1, CEK, FGFBR, FLG, FLT-2, FLT2, Fibroblast growth factor receptor 1, Fms-like tyrosine kinase 2, HBGFR, N-sam, Proto-oncogene c-Fgr, bFGF-R-1

    分子量

    91868 Da

    基因ID

    2260, 9606

    UniProt

    P11362

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, S100 Proteins
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