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- 抗原 See all PRDM2 抗体
- PRDM2 (PR Domain Containing 2, with ZNF Domain (PRDM2))
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抗原表位
- AA 1-347, N-Term
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适用
- 人, 小鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This PRDM2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 特异性
- This antibody is specific for RIZ1, it does not recognize the isoform beta (RIZ2).
- 产品特性
- Synonyms: PR domain zinc finger protein 2, KMT8, RIZ1, RIZ2, MTB-ZF, HUMHOXY1, Retinoblastomaprotein-interacting zinc finger protein, MTE-binding protein, GATA-3-binding protein G3B,Lysine N-methyltransferase 8
- 纯化方法
- Protein G Chromatography eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- 免疫原
- Purified recombinant GST fusion protein encoding aa 1-347 of human RIZ1.
- 克隆位点
- 33AT1045
- 亚型
- IgG1
- Top Product
- Discover our top product PRDM2 Primary Antibody
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anti-PR Domain Containing 2, with ZNF Domain (PRDM2) antibody
PRDM2 适用: 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-PR Domain Containing 2, with ZNF Domain (PRDM2) (AA 1-347) antibodyPRDM2 适用: 人, 小鼠 WB, ELISA, ChIP 宿主: 小鼠 Monoclonal 33AT1045 unconjugated
anti-PR Domain Containing 2, with ZNF Domain (PRDM2) (AA 1-347) antibodyPRDM2 适用: 人, 小鼠 WB, ChIP 宿主: 小鼠 Monoclonal 33AT1045 unconjugated
anti-PR Domain Containing 2, with ZNF Domain (PRDM2) (AA 1201-1300) antibodyPRDM2 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-PR Domain Containing 2, with ZNF Domain (PRDM2) antibodyPRDM2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-PR Domain Containing 2, with ZNF Domain (PRDM2) (AA 1-347) antibodyPRDM2 适用: 人 WB, IP 宿主: 小鼠 Monoclonal 33AT1045 unconjugated
anti-PR Domain Containing 2, with ZNF Domain (PRDM2) (AA 733-961) antibodyPRDM2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-PR Domain Containing 2, with ZNF Domain (PRDM2) (AA 245-573) antibodyPRDM2 适用: 大鼠 IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-PR Domain Containing 2, with ZNF Domain (PRDM2) antibodyPRDM2 适用: 人, 小鼠 WB, IP, ChIP 宿主: 小鼠 Monoclonal unconjugated
anti-PR Domain Containing 2, with ZNF Domain (PRDM2) (AA 1606-1705) antibodyPRDM2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
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ELISA: 1/1,000. Western blotting: 1/100-1/500. ChIP (validated by third-party citation).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.25 mg/mL
- 缓冲液
- PBS containing 0.09 % (W/V) Sodium Azide as preservative.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. - 有效期
- 12 months
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- 抗原
- PRDM2 (PR Domain Containing 2, with ZNF Domain (PRDM2))
- 别名
- PRDM2 (PRDM2 产品)
- 别名
- MGC114763 antibody, prdm2 antibody, riz antibody, kmt8 antibody, riz1 antibody, riz2 antibody, mtb-zf antibody, humhoxy1 antibody, PRDM2 antibody, HUMHOXY1 antibody, KMT8 antibody, MTB-ZF antibody, RIZ antibody, RIZ1 antibody, RIZ2 antibody, 4833427P12Rik antibody, E330024L24Rik antibody, Gm1033 antibody, Gm19732 antibody, Riz antibody, Riz1 antibody, Znfpr1c1 antibody, PR domain containing 2, with ZNF domain S homeolog antibody, PR domain containing 2, with ZNF domain b antibody, PR domain containing 2, with ZNF domain antibody, PR domain zinc finger protein 2 antibody, PR/SET domain 2 antibody, prdm2.S antibody, prdm2b antibody, prdm2 antibody, LOC100350859 antibody, PRDM2 antibody, Prdm2 antibody
- 背景
- Similar to acetylation and phosphorylation, histone methylation at the N-terminal tail has emerged as an important role in regulating chromatin dynamics and gene activity. Histone methylation occurs on arginine and lysine residues and is catalyzed by two families of proteins, the protein arginine methyltransferase family and the SET-domain-containing methyltransferase family. Five members have been identified in the arginine methyltransferase family. About 27 are grouped into the SET-domain family, and another 17 make up the PR domain family that is related to the SET domain family. The retinoblastoma protein-interacting zinc finger geneRIZ1 is a tumor suppressor gene and a FOUNDING member of the PR domain family. RIZ1 inactivation is commonly found in many types of human cancers and occurs through loss of mRNA expression, frame shift mutation, chromosomal deletion, and missense mutation. RIZ1 is also a tumor susceptibility gene in mice. The loss of RIZ1 mRNA in human cancers was shown to associate with DNA methylation of its promoter CpG island. Methylation of the RIZ1 promoter strongly correlated with lost or decreased RIZ1 mRNA expression in breast, liver, colon, and lung cancer cell lines as well as in liver cancer tissues.Synonyms: GATA-3-binding protein G3B, HUMHOXY1, KMT8, Lysine N-methyltransferase 8, MTB-ZF, MTE-binding protein, PR domain zinc finger protein 2, RIZ1, RIZ2, Retinoblastoma protein-interacting zinc finger protein
- 基因ID
- 7799
- UniProt
- Q13029
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