PRDM2 产品
(PR Domain Containing 2, with ZNF Domain (PRDM2))
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This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008].
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Featured PRDM2 Categories
Recommended PRDM2 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Application
IHC
Validations
- (5)
Cat. No.
ABIN7264615
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, ChIP
Validations
- (6)
Cat. No.
ABIN3032300
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ChIP
Validations
- (2)
- (4)
Cat. No.
ABIN387783
Quantity
400 μL
Datasheet
Datasheet
Recommended PRDM2 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6951135
Quantity
96 tests
Datasheet
Datasheet
Recommended PRDM2 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7124542
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1316143
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7317620
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our PRDM2 Products
: "DNA methylation of the RIZ1 tumor suppressor gene plays an important role in the tumorigenesis of cervical cancer." in: European journal of medical research, Vol. 15, Issue 1, pp. 20-4, (2010) (PubMed).: "Genotypes and haplotypes of the estrogen receptor genes, but not the retinoblastoma-interacting zinc finger protein 1 gene, are associated with osteoporosis." in: Calcified tissue international, Vol. 87, Issue 1, pp. 25-35, (2010) (PubMed).
: "RIZ1 is potential CML tumor suppressor that is down-regulated during disease progression." in: Journal of hematology & oncology, Vol. 2, pp. 28, (2009) (PubMed).
: "Genetic variants of methyl metabolizing enzymes and epigenetic regulators: associations with promoter CpG island hypermethylation in colorectal cancer." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 18, Issue 11, pp. 3086-96, (2009) (PubMed).
: "A histone methyltransferase is required for maximal response to female sex hormones." in: Molecular and cellular biology, Vol. 24, Issue 16, pp. 7032-42, (2004) (PubMed).
Synonyms and alternative names related to PRDM2
PR domain containing 2, with ZNF domain S homeolog (prdm2.S), PR domain containing 2, with ZNF domain b (prdm2b), PR domain containing 2, with ZNF domain (prdm2), PR domain zinc finger protein 2 (LOC100350859), PR/SET domain 2 (PRDM2), PR domain containing 2, with ZNF domain (Prdm2), PR/SET domain 2 (Prdm2), 4833427P12Rik, E330024L24Rik, Gm1033, Gm19732, humhoxy1, HUMHOXY1, kmt8, KMT8, MGC114763, mtb-zf, MTB-ZF, prdm2, PRDM2, riz, RIZ, Riz, riz1, RIZ1, Riz1, riz2, RIZ2, Znfpr1c1Protein level used designations for PRDM2
- PR domain containing 2, with ZNF domain
- retinoblastoma protein-binding zinc finger protein-like
- PR domain zinc finger protein 2-like
- GATA-3 binding protein G3B
- GATA-3-binding protein G3B
- MTE-binding protein
- PR domain zinc finger protein 2
- PR domain-containing protein 2
- lysine N-methyltransferase 8
- retinoblastoma protein-binding zinc finger protein
- retinoblastoma protein-interacting zinc finger protein
- zinc finger protein RIZ
- zinc-finger DNA-binding protein
- retinoblastoma interacting zinc finger protein
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