c-MET 抗体 (Catalytic Domain)
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Quick Overview for c-MET 抗体 (Catalytic Domain) (ABIN356339)
抗原
See all c-MET (MET) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- Catalytic Domain
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特异性
- This antibody detects MET/HGFR.
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交叉反应 (详细)
- Species reactivity (tested):Human and Mouse
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产品特性
- Synonyms: Hepatocyte growth factor receptor, MET, Scatter factor receptor, HGF/SF receptor, c-Met,Met proto-oncogene tyrosine kinase
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纯化方法
- Affinity chromatography on Protein G
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免疫原
- This monoclonal antibody is generated from mice immunized with purified recombinantprotein encoding the catalytic domain of human Met.
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亚型
- IgG1
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应用备注
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ELISA: 1/1,000Western blotting: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) Sodium Azide as preservative, 0.09 % (W/V) Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- c-MET (MET) (Met Proto-Oncogene (MET))
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别名
- HGF Receptor
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背景
- The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene.Synonyms: HGF/SF receptor, Hepatocyte growth factor receptor, MET, Met proto-oncogene tyrosine kinase, Scatter factor receptor, c-Met
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基因ID
- 4233
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UniProt
- P08581
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途径
- RTK signaling, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor
抗原
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