电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

CUL9 抗体 (C-Term)

CUL9 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN356104
发货至: 中国
  • 抗原 See all CUL9 抗体
    CUL9 (Cullin 9 (CUL9))
    抗原表位
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 18
    • 7
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 15
    • 4
    克隆类型
    • 15
    • 4
    多克隆
    标记
    • 19
    This CUL9 antibody is un-conjugated
    应用范围
    • 18
    • 9
    • 7
    • 6
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    affinity purified
    免疫原
    17 amino acid synthetic peptide from near the carboxy terminus of human PARC.
    亚型
    IgG
    Top Product
    Discover our top product CUL9 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    储存条件
    -20 °C
  • 抗原
    CUL9 (Cullin 9 (CUL9))
    别名
    PARC/P53-associated Parkin-like Cytoplasmic Protein (CUL9 产品)
    别名
    H7AP1 antibody, PARC antibody, RP3-330M21.2 antibody, parc antibody, 1810035I07Rik antibody, Cul-9 antibody, Parc antibody, mKIAA0708 antibody, RGD1562008 antibody, cullin-9 antibody, cullin 9 antibody, cullin-9 antibody, CUL9 antibody, LOC100083225 antibody, cul9 antibody, LOC100561099 antibody, Cul9 antibody
    背景
    PARC (p53 associated parkin like cytoplasmic protein) antibody directly interacted and formed an approximately 1MD complex with p53 in the cytoplasm of unstressed cells. In the absence of stress, inactivation of PARC induced nuclear localization of endogenous p53 and activated p53 dependent apoptosis. Overexpression of PARC promoted cytoplasmic sequestration of ectopic p53. Furthermore, abnormal cytoplasmic localization of p53 was observed in a number of neuroblastoma cell lines, RNA interference-mediated reduction of endogenous PARC significantly sensitized these neuroblastoma cells in the DNA damage response. These results revealed that PARC is a critical regulator in controlling p53 subcellular localization and subsequent function.
You are here:
客服