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CUL9 抗体 (C-Term)

CUL9 适用: 人, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN500449
发货至: 中国
  • 抗原 See all CUL9 抗体
    CUL9 (Cullin 9 (CUL9))
    抗原表位
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 18
    • 7
    • 2
    • 2
    人, 小鼠
    宿主
    • 15
    • 4
    克隆类型
    • 15
    • 4
    多克隆
    标记
    • 19
    This CUL9 antibody is un-conjugated
    应用范围
    • 18
    • 9
    • 8
    • 7
    • 4
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects Cullin-9.
    交叉反应 (详细)
    Species reactivity (tested):Human, mouse
    纯化方法
    Peptide affinity chromatography
    免疫原
    PARC antibody was raised against a 17 amino acid peptide from near the carboxy terminus of human PARC.
    亚型
    IgG
    Top Product
    Discover our top product CUL9 Primary Antibody
  • 应用备注
    ELISA. Western blot. Immuncytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    CUL9 (Cullin 9 (CUL9))
    别名
    Cullin-9 (CUL9 产品)
    别名
    H7AP1 antibody, PARC antibody, RP3-330M21.2 antibody, parc antibody, 1810035I07Rik antibody, Cul-9 antibody, Parc antibody, mKIAA0708 antibody, RGD1562008 antibody, cullin-9 antibody, cullin 9 antibody, cullin-9 antibody, CUL9 antibody, LOC100083225 antibody, cul9 antibody, LOC100561099 antibody, Cul9 antibody
    背景
    The continued localization of p53 to the nucleus is essential for its function as a tumor suppressor. PARC, a large, Parkin-like ubiquitin ligase has recently been identified as a cytoplasmic anchor protein in p53-associated protein complexes. In the absence of stress, PARC inactivation results in nuclear localization of p53 and activation of p53-dependent apoptosis, while overexpression of this protein promoted cytoplasmic sequestration of p53. Surprisingly, PARC knockout mice were viable and exhibited no obvious phenotype, suggesting that other proteins, such as the highly related cullin family of E3 ubiquitin ligases, may perform similar functions in the absence of PARC. Additionally, it has been suggested that p53 binding to PARC may serve to control PARC function.Synonyms: CUL-9, H7AP1, KIAA0708, PARC, UbcH7-associated protein 1, p53-associated parkin-like cytoplasmic protein
    基因ID
    23113
    NCBI登录号
    NP_055904
    UniProt
    Q8IWT3
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