SORL1 抗体 (C-Term)
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- 抗原 See all SORL1 抗体
- SORL1 (Sortilin-Related Receptor, L(DLR Class) A Repeats Containing (SORL1))
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抗原表位
- C-Term
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SORL1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 特异性
- Specific for SORLA.
- 交叉反应
- 小鼠
- 交叉反应 （详细）
- Other species not yet tested.
- 纯化方法
- IgG
- 免疫原
- A synthetic peptide from c-terminal of mouse SorLA conjugated to blue carrier protein was used as the antigen.
- 亚型
- IgG
- Top Product
- Discover our top product SORL1 Primary Antibody
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anti-Sortilin-Related Receptor, L(DLR Class) A Repeats Containing (SORL1) antibody
SORL1 适用: 人 ELISA, WB, IHC, ICC 宿主: 小鼠 Monoclonal 3B6B11 unconjugated
anti-Sortilin-Related Receptor, L(DLR Class) A Repeats Containing (SORL1) (C-Term) antibodyVerified SORL1 适用: 人 ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Sortilin-Related Receptor, L(DLR Class) A Repeats Containing (SORL1) (AA 652-665), (Extracellular), (N-Term) antibodySORL1 适用: 人, 小鼠, 大鼠 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Sortilin-Related Receptor, L(DLR Class) A Repeats Containing (SORL1) (AA 2001-2100) antibodySORL1 适用: 人 ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Sortilin-Related Receptor, L(DLR Class) A Repeats Containing (SORL1) (AA 82-181) antibodySORL1 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 3F2 unconjugated
anti-Sortilin-Related Receptor, L(DLR Class) A Repeats Containing (SORL1) (AA 2159-2214) antibodySORL1 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 7D7B11 unconjugated
anti-Sortilin-Related Receptor, L(DLR Class) A Repeats Containing (SORL1) (AA 525-744) antibodySORL1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sortilin-Related Receptor, L(DLR Class) A Repeats Containing (SORL1) (AA 82-181) antibodySORL1 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Sortilin-Related Receptor, L(DLR Class) A Repeats Containing (SORL1) (AA 2065-2214) antibodySORL1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.
- 注意事项
- Avoid freeze and thaw cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
- 有效期
- 12 months
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- 抗原
- SORL1 (Sortilin-Related Receptor, L(DLR Class) A Repeats Containing (SORL1))
- 别名
- SorLA (SORL1 产品)
- 别名
- SORL1 antibody, C11orf32 antibody, LR11 antibody, LRP9 antibody, SORLA antibody, SorLA-1 antibody, gp250 antibody, SorLA antibody, 2900010L19Rik antibody, AI596264 antibody, AW261561 antibody, mSorLA antibody, Lr11 antibody, RGD619914 antibody, sortilin related receptor 1 antibody, sortilin-related receptor antibody, sortilin-related receptor, L(DLR class) A repeats containing antibody, sortilin-related receptor, L(DLR class) A repeats-containing antibody, sortilin-related receptor, LDLR class A repeats-containing antibody, sorl1 antibody, LOC582560 antibody, SORL1 antibody, Sorl1 antibody
- 背景
- FUNCTION: Likely to be a multifunctional endocytic receptor, that may be implicated in the uptake of lipoproteins and of proteases. Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. Binds the receptor-associated protein (RAP). Could play a role in cell-cell interaction. May play a role in neural organization, as well as the establishment of embryonic organ systems. SUBCELLULAR LOCATION: Membrane, Single-pass type I membrane protein. TISSUE SPECIFICITY: Abundant in brain, where it is mainly expressed in adult cerebellum, hippocampal ca regions, dentate gyrus, and to a much lesser extent in the cerebral cortex. Detectable in kidney, skeletal muscle, lung and spleen, but not in the liver. DEVELOPMENTAL STAGE: Expressed as early as embryonic day 6.5 (E6.5) and peaks at E11, the main location is in the CNS during development. At early stages, it is abundant in a subpopulation of neurons in the cerebral cortex, in the hippocampus, and granular and Purkinje cell layers in the cerebellum, whereas in the adult, expression in cerebellar granular cells and in the cerebral cortex is low. Expression occurs also in a variety of glands and organs during organogenesis.,Neurodegeneration,Sortilin-related receptor, Sortilin related receptor, Sorting protein related receptor containing LDLR class A repeats, mSorLA, SorLA-1, Low density lipoprotein receptor relative with 11 ligand-binding repeats, LDLR relative with 11 ligand binding repeats, LR11, Gp250, SORL
- UniProt
- O88307
- 途径
- Smooth Muscle Cell Migration
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