CD14 抗体
Quick Overview for CD14 抗体 (ABIN343172)
抗原
See all CD14 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Protein G purified
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免疫原
- Monocytes and immunoaffinity purified soluble CD14
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亚型
- IgG1
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应用备注
- Suitable for immunostaining of CD14 positive cells, (Flow cytometry), ELISA, Suitable for Western blot (non reducing). Non inhibition of LPS binding to CD14, binding epitope: amino acid 9-13, 39-44, Binding titre: 1:10.000
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限制
- 仅限研究用
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状态
- Lyophilized
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浓度
- 1 mg/ml
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缓冲液
- 0.1 mg/100 ul PBS without NaN3
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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Role of the lipopolysaccharide-CD14 complex for the activity of hemolysin from uropathogenic Escherichia coli." in: Infection and immunity, Vol. 75, Issue 2, pp. 997-1004, (2007) (PubMed).
: "Escherichia coli Braun lipoprotein induces a lipopolysaccharide-like endotoxic response from primary human endothelial cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 167, Issue 9, pp. 5231-9, (2001) (PubMed).
: "Structures in Bacillus subtilis are recognized by CD14 in a lipopolysaccharide binding protein-dependent reaction." in: Infection and immunity, Vol. 67, Issue 6, pp. 2964-8, (1999) (PubMed).
: "Binding of bacterial peptidoglycan to CD14." in: The Journal of biological chemistry, Vol. 273, Issue 15, pp. 8680-90, (1998) (PubMed).
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Role of the lipopolysaccharide-CD14 complex for the activity of hemolysin from uropathogenic Escherichia coli." in: Infection and immunity, Vol. 75, Issue 2, pp. 997-1004, (2007) (PubMed).
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- CD14
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别名
- CD14
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背景
- BiG 7 represents an excellent marker for CD14. The CD14 glycoprotein, gp 55, is present on most monocytic and macrophages like cell types: monocytes, macrophages, Kupffer cells, pleural phagocytic cells and dendritic reticular cells. CD14 is also observed on granulocytes and activated or transformed B-cells. Furthermore CD14 is present in a soluble form in human serum, urine and other body fluids. The CD14 molecule has been reported to be a receptor for endotoxin.
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途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
抗原
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