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CD14 抗体

This anti-CD14 antibody is a 小鼠 单克隆 antibody detecting CD14 in FACS, WB, ELISA 和 Func. Suitable for 人. This Primary Antibody has been cited in 4+ publications.
产品编号 ABIN343172
发货至: 中国

Quick Overview for CD14 抗体 (ABIN343172)

抗原

See all CD14 抗体
CD14

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD14 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Western Blotting (WB), ELISA, Functional Studies (Func)

克隆位点

BiG 7
  • 纯化方法

    Protein G purified

    免疫原

    Monocytes and immunoaffinity purified soluble CD14

    亚型

    IgG1
  • 应用备注

    Suitable for immunostaining of CD14 positive cells, (Flow cytometry), ELISA, Suitable for Western blot (non reducing). Non inhibition of LPS binding to CD14, binding epitope: amino acid 9-13, 39-44, Binding titre: 1:10.000

    限制

    仅限研究用
  • 状态

    Lyophilized

    浓度

    1 mg/ml

    缓冲液

    0.1 mg/100 ul PBS without NaN3

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C
  • Muansson, Kjaell, Pellett, Nagy, Welch, Baeckhed, Frisan, Richter-Dahlfors: "Role of the lipopolysaccharide-CD14 complex for the activity of hemolysin from uropathogenic Escherichia coli." in: Infection and immunity, Vol. 75, Issue 2, pp. 997-1004, (2007) (PubMed).

    Neilsen, Zimmerman, McIntyre: "Escherichia coli Braun lipoprotein induces a lipopolysaccharide-like endotoxic response from primary human endothelial cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 167, Issue 9, pp. 5231-9, (2001) (PubMed).

    Fan, Stelter, Menzel, Jack, Spreitzer, Hartung, Schuett: "Structures in Bacillus subtilis are recognized by CD14 in a lipopolysaccharide binding protein-dependent reaction." in: Infection and immunity, Vol. 67, Issue 6, pp. 2964-8, (1999) (PubMed).

    Dziarski, Tapping, Tobias: "Binding of bacterial peptidoglycan to CD14." in: The Journal of biological chemistry, Vol. 273, Issue 15, pp. 8680-90, (1998) (PubMed).

  • 抗原

    CD14

    别名

    CD14

    背景

    BiG 7 represents an excellent marker for CD14. The CD14 glycoprotein, gp 55, is present on most monocytic and macrophages like cell types: monocytes, macrophages, Kupffer cells, pleural phagocytic cells and dendritic reticular cells. CD14 is also observed on granulocytes and activated or transformed B-cells. Furthermore CD14 is present in a soluble form in human serum, urine and other body fluids. The CD14 molecule has been reported to be a receptor for endotoxin.

    途径

    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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