CD14 抗体 (AA 9-13, AA 39-44)
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Quick Overview for CD14 抗体 (AA 9-13, AA 39-44) (ABIN343167)
抗原
See all CD14 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 9-13, AA 39-44
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特异性
- Soluble and membrane bound human CD14. The antibody blocks LPS binding to membrane bound CD14
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交叉反应
- Corynebacterium diphtheriae, 牛, 马
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交叉反应 （详细）
- horse and bovine CD14,inhibits binding of LPS to horse and bovine CD14. Binding titre at horse CD14 1:100 and inhibition titre 1:10.
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纯化方法
- Protein A affinity column
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免疫原
- Monocytes of different species and immunoaffinity purified soluble human CD14
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亚型
- IgG1
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anti-CD14 (CD14) (AA 20-214) antibody
CD14 适用: 人, 小鼠 FACS, WB, IHC, ELISA 宿主: 小鼠 Monoclonal 4B4F12 unconjugated
anti-CD14 (CD14) (AA 20-214) antibodyCD14 适用: 人 IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 1H5D8 unconjugated
anti-CD14 (CD14) antibodyCD14 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 1A3B6 unconjugated
anti-CD14 (CD14) (AA 20-345) antibodyCD14 适用: 人 FACS, WB, IHC, IF, ELISA 宿主: 小鼠 Monoclonal 14G1F3 unconjugated
anti-CD14 (CD14) (AA 25-148) antibodyCD14 适用: 人 FACS, WB, IHC, ISt, StM 宿主: 小鼠 Monoclonal LPSR-2385 unconjugated
anti-CD14 (CD14) (AA 230-345) antibodyCD14 适用: 人 FACS, WB, IHC, ELISA 宿主: 小鼠 Monoclonal 1D1F8 unconjugated
anti-CD14 (CD14) (AA 54-83), (N-Term) antibodyCD14 适用: 人 FACS, WB, IF, IHC (p) 宿主: 兔 Polyclonal RB14105 unconjugated
anti-CD14 (CD14) (AA 201-300) antibodyCD14 适用: 人, 小鼠, 大鼠, 绵羊, 犬, 兔 WB, ELISA, ICC, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-CD14 (CD14) (Internal Region) antibodyVerified CD14 适用: 人 FACS, WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-CD14 (CD14) (AA 25-148) antibodyCD14 适用: 人 WB, IHC, ISt, StM 宿主: 小鼠 Monoclonal LPSR-2397 unconjugated
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应用备注
- total inhibition of LPS-binding to CD14: 100 μg/mL. Binding titre at human CD14 transfected CHO-cells: more than 10.000.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstitute with bidistilled water
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4
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储存液
- Without preservative
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储存条件
- -20 °C,-80 °C
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: "Analysis of CD14 Expression Levels in Putative Mesenchymal Progenitor Cells Isolated from Equine Bone Marrow." in: Stem cells and development, (2010) (PubMed).
: "Young foal and adult horse monocyte-derived dendritic cells differ by their degree of phenotypic maturity." in: Veterinary immunology and immunopathology, Vol. 131, Issue 1-2, pp. 1-8, (2009) (PubMed).
: "The myeloid differentiation antigen CD14 is N- and O-glycosylated. Contribution of N-linked glycosylation to different soluble CD14 isoforms." in: European journal of biochemistry / FEBS, Vol. 236, Issue 2, pp. 457-64, (1996) (PubMed).
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: "Analysis of CD14 Expression Levels in Putative Mesenchymal Progenitor Cells Isolated from Equine Bone Marrow." in: Stem cells and development, (2010) (PubMed).
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- CD14
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别名
- CD14
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背景
- Background: biG 10 represents an excellent marker for CD14. The CD14 glycoprotein, gp 55, is present on most monocytic and macrophages like cell types: monocytes, macrophages, weekly at surface of neutrophiles like Kupffer cells, pleural phagocytic cells and dendritic reticular cells. CD14 is also observed on granulocytes and activated or transformed B-cells. Furthermore CD14 is present in a soluble form in human serum, urine and other body fluids. The CD14 Molecule has been reported to be a receptor for endotoxin. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor for LPS-LBP (lipopolysaccharide binding protein)-complexes.
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分子量
- ~50kDa
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基因ID
- 929
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NCBI登录号
- NP_000582
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UniProt
- P08571
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途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
抗原
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