FGFR1 抗体 (AA 152-156)
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- 抗原 See all FGFR1 抗体
- FGFR1 (Fibroblast Growth Factor Receptor 1 (FGFR1))
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抗原表位
- AA 152-156
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FGFR1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- This antibody detects endogenous levels of total FGF Receptor 1 (CD331/FGFR1) protein.
- 纯化方法
- Immunoaffinity Chromatography using epitope-specific peptide
- 免疫原
- Peptide sequence around amino acids 152-156 (A-P-Y-W-T) derived from FGF Receptor 1 Human.
- Top Product
- Discover our top product FGFR1 Primary Antibody
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anti-Fibroblast Growth Factor Receptor 1 (FGFR1) (AA 19-48), (N-Term) antibody
FGFR1 适用: 人, 小鼠 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB04521 unconjugated
anti-Fibroblast Growth Factor Receptor 1 (FGFR1) (AA 236-362) antibodyFGFR1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor 1 (FGFR1) (C-Term) antibodyFGFR1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor 1 (FGFR1) (AA 19-48) antibodyFGFR1 适用: 人, 小鼠 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor 1 (FGFR1) (AA 31-150) antibodyFGFR1 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 5E9 unconjugated
anti-Fibroblast Growth Factor Receptor 1 (FGFR1) (pTyr766) antibodyFGFR1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor 1 (FGFR1) (Tyr766) antibodyFGFR1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor 1 (FGFR1) (AA 291-324) antibodyFGFR1 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB50848 unconjugated
anti-Fibroblast Growth Factor Receptor 1 (FGFR1) (AA 806-842), (C-Term) antibodyFGFR1 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Monoclonal 1440CT772-50-23 unconjugated
anti-Fibroblast Growth Factor Receptor 1 (FGFR1) antibodyFGFR1 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Monoclonal 4C3 unconjugated
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- 应用备注
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Western Blot (1/500-1/1000). Incubate membrane with diluted antibody in 5 % nonfat milk, 1X TBSS, 0.1 % Tween-20 at4 °C with gentle shaking, overnight.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Store the antibody (in aliquots) at-20 °C.
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- 抗原
- FGFR1 (Fibroblast Growth Factor Receptor 1 (FGFR1))
- 别名
- FGFR1 (FGFR1 产品)
- 别名
- FGFR antibody, fgfr antibody, X1FGFR antibody, XFGFR-1 antibody, XFGFRA2 antibody, bfgfr antibody, cek antibody, fgfr1 antibody, flg antibody, flt-2 antibody, flt2 antibody, kal2 antibody, ogd antibody, xfgfr1 antibody, CG7223 antibody, CT22273 antibody, CT39172 antibody, DFGF-R1 antibody, DFGF-R2 antibody, DFR-1 antibody, DFR1 antibody, DFR1/DFGF-R2 antibody, DPR3 antibody, DTRK(FR1) antibody, Dfr-1 antibody, Dfr1 antibody, DmHD-38 antibody, Dmel\\CG7223 antibody, Dtk1 antibody, EMS2 antibody, FGF-R2 antibody, FGFR2 antibody, FR1 antibody, Fr1 antibody, HD-38 antibody, HTL/FGFR1 antibody, Htl antibody, Tk1 antibody, dtk1 antibody, i100 antibody, i150 antibody, i79 antibody, j372 antibody, cd331 antibody, fgfbr antibody, fgfr-1 antibody, hbgfr antibody, n-sam antibody, ach antibody, cd333 antibody, cek2 antibody, fgfr-3 antibody, hsfgfr3ex antibody, jtk4 antibody, BFGFR antibody, CD331 antibody, CEK antibody, FGFBR antibody, FGFR-1 antibody, FLG antibody, FLT-2 antibody, FLT2 antibody, HBGFR antibody, HH2 antibody, KAL2 antibody, N-SAM antibody, OGD antibody, bFGF-R-1 antibody, AW208770 antibody, Eask antibody, Fgfr-1 antibody, Flt-2 antibody, Hspy antibody, FLG-1 antibody, FGFRI antibody, x1fgfr antibody, cb231 antibody, sb:cb231 antibody, fibroblast growth factor receptor antibody, fibroblast growth factor receptor 1 S homeolog antibody, basic fibroblast growth factor receptor 1 antibody, heartless antibody, fibroblast growth factor receptor 1 antibody, fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) L homeolog antibody, Fibroblast growth factor receptor 1 antibody, fibroblast growth factor receptor 1 L homeolog antibody, fibroblast growth factor receptor 1a antibody, FGFR antibody, fgfr antibody, fgfr1.S antibody, CpipJ_CPIJ005849 antibody, htl antibody, fgfr1 antibody, fgfr3.L antibody, FGFR1 antibody, Fgfr1 antibody, fgfr1.L antibody, fgfr1a antibody
- 背景
- FGFR1 (fibroblast growth factor receptor 1) is a member of the fibroblast growth factor receptor family and contains an Ig-like domain and a tyrosine kinase domain. This receptor has multiple isoforms and is a Type I membrane protein. FGFR1 is widely expressed, with distinct isoforms expressed in specific tissues. FGFR1 binds fibroblast growth factor and induces mitogenesis and cellular differentiation. Defects in FGFR1 result in Pfeiffer syndrome associated with craniosynostosis. FGFR1 can be modified by phosphorylation and can bind basic/acidic fibroblast factor depending on the receptor isoform. FGFR1 has been shown to interact with N-cadherin and NCAM. At the mRNA level, FGFR1 is highly expressed in developing human tissues including the brain (preferentially in neurons), vascular basement membranes, skin, and bone growth plates. It may be found in most anchorage dependent cells on their membrane and also may be localized around and in nuclei. Pfeiffer syndrome, as well as other disorders of human skeletal development, is the result of a mutation in the extracellular domain of FGFR1.Synonyms: BFGFR, Basic fibroblast growth factor receptor 1, CEK, FGFBR, FLG, FLT-2, FLT2, Fibroblast growth factor receptor 1, Fms-like tyrosine kinase 2, HBGFR, N-sam, Proto-oncogene c-Fgr, bFGF-R-1
- 分子量
- 145 kDa
- 基因ID
- 2260
- NCBI登录号
- NP_001167534
- UniProt
- P11362
- 途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, S100 Proteins
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