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PTK7 抗体 (N-Term)

PTK7 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN318893
发货至: 中国
  • 抗原 See all PTK7 抗体
    PTK7 (PTK7 Protein tyrosine Kinase 7 (PTK7))
    抗原表位
    • 19
    • 8
    • 8
    • 6
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 60
    • 21
    • 8
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    人, 小鼠, 大鼠
    宿主
    • 49
    • 9
    • 2
    • 1
    克隆类型
    • 52
    • 9
    多克隆
    标记
    • 39
    • 6
    • 5
    • 4
    • 4
    • 3
    This PTK7 antibody is un-conjugated
    应用范围
    • 51
    • 37
    • 24
    • 13
    • 9
    • 8
    • 5
    • 4
    • 4
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody recognises Protein tyrosine kinase-like 7 (PTK7).
    纯化方法
    Antisera to human PTK7 (NT) were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography.
    免疫原
    A 15 amino acid peptide located near the N-terminal region of human PTK7.
    亚型
    IgG
    Top Product
    Discover our top product PTK7 Primary Antibody
  • 应用备注
    Western Blot: 0.5 - 1.0g/mL, detects a band of approximately 86 kDa in colon tissuelysates.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline containing 0.02 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    PTK7 (PTK7 Protein tyrosine Kinase 7 (PTK7))
    别名
    PTK7 / CCK4 (PTK7 产品)
    别名
    PTK7 antibody, CCK-4 antibody, CCK4 antibody, Srf antibody, 8430404F20Rik antibody, chz antibody, mPTK7/CCK4 antibody, KLG antibody, protein tyrosine kinase 7 (inactive) antibody, protein tyrosine kinase 7 antibody, PTK7 protein tyrosine kinase 7 antibody, PTK7 antibody, Ptk7 antibody
    背景
    PTK7 is a member of the receptor tyrosine kinase family, otherwise known as Colon Carcinoma Kinase 4 (CCK4). PTK7 is highly expressed in the kidney, liver, lung, pancreas and melanocytes with weaker expression being detected in the thyroid gland, ovaries, brain, heart and skeletal muscle. PTK7 may play a role in embryonic development. It is thought to function as a cell adhesion molecule and as a novel regulator of the planar cell polarity (PCP) pathway in vertebrates. Studies also suggest that PTK7 may be involved in the tumour progression. A loss of PTK7 expression has been observed in melanoma cell lines, whereas increased levels of PTK7 have been detected in high-throughput acute myeloid leukaemia samples. In addition, PTK7 is not expressed in normal colon but has been detected in colon carcinomas and as such is a potential marker for tumour progression.Synonyms: CCK-4, Colon carcinoma kinase 4, Tyrosine-protein kinase-like 7
    基因ID
    5754
    NCBI登录号
    NP_002812
    UniProt
    Q13308
    途径
    RTK signaling, Tube Formation
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