SH2B3 抗体 (N-Term)
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- 抗原 See all SH2B3 抗体
- SH2B3 (SH2B Adaptor Protein 3 (SH2B3))
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抗原表位
- N-Term
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适用
- 人
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宿主
- 山羊
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克隆类型
- 多克隆
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标记
- This SH2B3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- This antibody recognises an epitope within the N-terminal region (NT) of lymphocyte adaptor protein (LNK).
- 纯化方法
- Antisera to LNK (NT) were raised by repeated immunisation of Goat with highly purified antigen. Purified IgG prepared by affinity chromatography.
- 免疫原
- Peptide sequence NGPALQPSSPC from LNK amino-terminus.
- 亚型
- IgG
- Top Product
- Discover our top product SH2B3 Primary Antibody
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anti-SH2B Adaptor Protein 3 (SH2B3) (AA 67-101) antibody
SH2B3 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB57762 unconjugated
anti-SH2B Adaptor Protein 3 (SH2B3) (N-Term) antibodyVerified SH2B3 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-SH2B Adaptor Protein 3 (SH2B3) (N-Term) antibodySH2B3 适用: 人 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-SH2B Adaptor Protein 3 (SH2B3) (AA 225-447) antibodySH2B3 适用: 小鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western Blot: 0.3 - 1.0g/mL, detects a band of approximately 70 kDa in human MOLT4 celllysates. (Predicted Mwt.63.0 kDa)
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 0.5mg/mL
- 缓冲液
- TRIS buffered saline containing 0.02 % Sodium Azide and 0.5 % Bovine Serum Albumin
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- SH2B3 (SH2B Adaptor Protein 3 (SH2B3))
- 别名
- SH2B3 (SH2B3 产品)
- 别名
- LNK antibody, IDDM20 antibody, AI429800 antibody, Lnk antibody, SH2B adaptor protein 3 antibody, SH2B3 antibody, Sh2b3 antibody
- 背景
- LNK is an SH2-containing adaptor protein, which regulates cytokine receptor-mediated and growth factor pathways, and plays an essential role in B cell lymphopoiesis. LNK mRNA is preferentially expressed in lymph node and spleen lymphocytes and the expression of LNK in vascular endothelial cells (ECs), increases in response to TNFalpha. The role of LNK as a negative regulator, includes the down regulation of the pro-inflammatory molecules VCAM-1 and E-selectin induced by TNFalpha, modulation of P13-kinase and MAPK ERK1/2 activity, and negative regulation of Thrombopoietin-mediated cell proliferation and endomitosis in hematopoietic cell lines.Synonyms: LNK, Lymphocyte adapter protein, Lymphocyte-specific adapter protein Lnk, SH2B adapter protein 3, SH2B3, Signal transduction protein Lnk
- 基因ID
- 10019
- NCBI登录号
- NP_005466
- UniProt
- Q9UQQ2
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