Prostacyclin Receptor 抗体
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- 抗原 See all Prostacyclin Receptor (PTGIR) 抗体
- Prostacyclin Receptor (PTGIR)
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Prostacyclin Receptor antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 特异性
- IP Receptor antibody detects endogenous levels of IP Receptor protein.(region surrounding His237)
- 纯化方法
- Affinity chromatography
- Top Product
- Discover our top product PTGIR Primary Antibody
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anti-Prostacyclin Receptor (PTGIR) (AA 207-386) antibody
PTGIR 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Prostacyclin Receptor (PTGIR) (AA 296-386) antibodyPTGIR 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 4B10 unconjugated
anti-Prostacyclin Receptor (PTGIR) (AA 296-387) antibodyPTGIR 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4B10 unconjugated
anti-Prostacyclin Receptor (PTGIR) antibodyPTGIR 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Prostacyclin Receptor (PTGIR) (N-Term) antibodyPTGIR 适用: 人, 猴, 兔 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Prostacyclin Receptor (PTGIR) antibodyPTGIR 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Prostacyclin Receptor (PTGIR) (3rd Extracellular Loop), (AA 290-302) antibodyPTGIR 适用: 人, 小鼠, 大鼠 WB, FACS 宿主: 兔 Polyclonal unconjugated
anti-Prostacyclin Receptor (PTGIR) antibodyPTGIR 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Prostacyclin Receptor (PTGIR) (AA 198-247) antibodyPTGIR 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1,0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- Prostacyclin Receptor (PTGIR)
- 别名
- Prostacyclin Receptor / PTGIR (PTGIR 产品)
- 别名
- IP antibody, PGI2 antibody, PRIPR antibody, prostaglandin I receptor (IP) antibody, prostaglandin I2 receptor antibody, Ptgir antibody, PTGIR antibody
- 背景
- Cyclooxygenases metabolize arachidonate to five primary prostanoids: PGE2, PGF2α, PGI2, TXA2 and PGD2. These lipid mediators interact with specific members of G protein-coupled prostanoid receptors, designated EP, FP, IP, TP and DP, respectively. The IP Receptor binds prostacyclin, PGI2, the main prostanoid synthesized by vascular tissues. First discovered in 1976, prostacyclin is involved in platelet aggregation inhibition, vasodilatation and cytoprotection, and either prostacyclin or its analogs are used in the treatment of hypertension. Upon binding to the IP Receptor, prostacyclin activates adenylate cyclase primarily through the Gas protein. The gene encoding the human IP Receptor is located on chromosome 19. It is expressed as a glycosylated and phosphorylated protein, which is abundantly expressed in vascular tissues such as aorta, lung, atrium and ventricle, as well as in kidney, thymus, spleen and neurons.Synonyms: PGI receptor, PRIPR, Prostaglandin I2 receptor, Prostanoid IP receptor
- 分子量
- approx. 45 kDa
- 基因ID
- 5739
- NCBI登录号
- NP_000951
- UniProt
- P43119
- 途径
- cAMP Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Thromboxane A2 Receptor Signaling
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