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GRID2 抗体

GRID2 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN317812
发货至: 中国
  • 抗原 See all GRID2 抗体
    GRID2 (Glutamate Receptor, Ionotropic, delta 2 (GRID2))
    适用
    • 16
    • 13
    • 13
    • 2
    人, 小鼠, 大鼠
    宿主
    • 14
    • 2
    克隆类型
    • 15
    • 1
    多克隆
    标记
    • 9
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GRID2 antibody is un-conjugated
    应用范围
    • 9
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    特异性
    This antibody detects endogenous levels of GluR delta-2 protein.(region surrounding Gly860)
    纯化方法
    Affinity Chromatography using epitope-specific immunogen.
    Top Product
    Discover our top product GRID2 Primary Antibody
  • 应用备注
    ELISA: 1/20000 - 1/40000. Western Blot: 1/500 - 1/1000. Immunofluorescence: 1/50 - 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH ~7.2 with 0.05 % Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    GRID2 (Glutamate Receptor, Ionotropic, delta 2 (GRID2))
    别名
    Glutamate Receptor delta-2 (GRID2 产品)
    别名
    GluD2 antibody, glurd2 antibody, si:rp71-1l7.1 antibody, GRID2 antibody, B230104L07Rik antibody, GluRdelta2 antibody, Lc antibody, Lc antibody, MMS10-AC antibody, Ms10ac antibody, cpr antibody, ho antibody, nmf408 antibody, tpr antibody, glutamate receptor, ionotropic, delta 2 antibody, glutamate receptor ionotropic, delta-2 antibody, glutamate ionotropic receptor delta type subunit 2 antibody, grid2 antibody, LOC704787 antibody, GRID2 antibody, Grid2 antibody, LOC536367 antibody
    背景
    Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamategated, cation-specific ion channels. Kainate/AMPA receptors co-localize with NMDA receptors in many synapses and consist of seven structurally related subunits, designated GluR-1 to -7, as well as GluR-δ2. The kainate/AMPA receptors are primarily responsible for the fast excitatory neurotransmission by glutamate whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions. The NMDA receptors consist of five subunits: ε1, 2, 3, 4 and one ζ subunit. The ζ subunit is expressed throughout the brainstem whereas the four ε subunits display limited distribution. In mice, mutations in the gene encoding GluR-δ2 (GRID2) cause the Lurcher phenotype. The gene encoding human GluR-δ2 maps to chromosome 4q22.Synonyms: GLURD2, GRID2, GluR delta-2
    分子量
    approx. 113 kDa
    基因ID
    2895
    NCBI登录号
    NP_001501
    UniProt
    O43424
    途径
    Synaptic Membrane
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