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GRID2 抗体 (AA 831-880)

This 兔 多克隆 antibody specifically detects GRID2 in WB, IF 和 ELISA. It exhibits reactivity toward 人, 大鼠 和 小鼠.
产品编号 ABIN1534413
发货至: 中国
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Quick Overview for GRID2 抗体 (AA 831-880) (ABIN1534413)

抗原

See all GRID2 抗体
GRID2 (Glutamate Receptor, Ionotropic, delta 2 (GRID2))

适用

  • 31
  • 29
  • 28
  • 2
人, 大鼠, 小鼠

宿主

  • 30
  • 2
兔

克隆类型

  • 31
  • 1
多克隆

标记

  • 15
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This GRID2 antibody is un-conjugated

应用范围

  • 23
  • 15
  • 11
  • 9
  • 6
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB), Immunofluorescence (IF), ELISA
  • 抗原表位

    • 14
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    AA 831-880

    原理

    GluR-δ2 Antibody

    特异性

    GluR-δ2 Polyclonal Antibody detects endogenous levels of GluR-δ2 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human GRID2. AA range:831-880

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    GRID2 (Glutamate Receptor, Ionotropic, delta 2 (GRID2))

    别名

    GRID2

    背景

    Synonyms: GRID2; GLURD2; Glutamate receptor delta-2 subunit; GluR delta-2 subunit

    Background: The protein encoded byThis gene is a member of the family of ionotropic glutamate receptors which are the predominant excitatory neurotransmitter receptors in the mammalian brain. The encoded protein is a multi-pass membrane protein that is expressed selectively in cerebellar Purkinje cells. A point mutation in the mouse ortholog, associated with the phenotype named 'lurcher', in the heterozygous state leads to ataxia resulting from selective, cell-autonomous apoptosis of cerebellar Purkinje cells during postnatal development. Mice homozygous for this mutation die shortly after birth from massive loss of mid- and hindbrain neurons during late embryogenesis. This protein also plays a role in synapse organization between parallel fibers and Purkinje cells. Alternate splicing results in multiple transcript variants encoding distinct isoforms. Mutations in this

    Gene Name: GRID2

    Protein Name: Glutamate receptor delta-2 subunit

    分子量

    113 kDa

    基因ID

    2895

    OMIM

    602368

    UniProt

    O43424

    途径

    Synaptic Membrane
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