GRID2 抗体 (AA 800-880)
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北京 101111
Quick Overview for GRID2 抗体 (AA 800-880) (ABIN7221306)
抗原
See all GRID2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 800-880
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原理
- Rabbit Anti-GluR-δ2 Polyclonal Antibody
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特异性
- GluR-δ2 Polyclonal Antibody detects endogenous levels of GluR-δ2 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from the C-terminal region of human GluR-delta2 at AA range: 800-880
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亚型
- IgG
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anti-Glutamate Receptor, Ionotropic, delta 2 (GRID2) (N-Term) antibody
GRID2 适用: 人, 大鼠, 小鼠 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, delta 2 (GRID2) (C-Term) antibodyGRID2 适用: 人, 大鼠, 小鼠 WB, IF, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, delta 2 (GRID2) (AA 908-1007) antibodyGRID2 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1A1 unconjugated
anti-Glutamate Receptor, Ionotropic, delta 2 (GRID2) (C-Term) antibodyGRID2 适用: 人 WB, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, delta 2 (GRID2) (C-Term) antibodyGRID2 适用: 人, 大鼠, 小鼠 WB, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, delta 2 (GRID2) (AA 908-1007) antibodyGRID2 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, delta 2 (GRID2) (AA 206-218), (Extracellular), (N-Term) antibodyGRID2 适用: 大鼠 WB, IF, IHC, IC, LCI 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IF 1:200-1:1000,ELISA 1:20000,Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- GRID2 (Glutamate Receptor, Ionotropic, delta 2 (GRID2))
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别名
- GluR-delta2
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背景
- GRID2, GLURD2, Glutamate receptor delta-2 subunit, GluR delta-2 subunitThe glutamate ionotropic receptor delta type subunit 2 encoded by GRID2 is a member of the family of ionotropic glutamate receptors which are the predominant excitatory neurotransmitter receptors in the mammalian brain. The encoded protein is a multi-pass membrane protein that is expressed selectively in cerebellar Purkinje cells. A point mutation in the mouse ortholog, associated with the phenotype named 'lurcher', in the heterozygous state leads to ataxia resulting from selective, cell-autonomous apoptosis of cerebellar Purkinje cells during postnatal development. Mice homozygous for this mutation die shortly after birth from massive loss of mid- and hindbrain neurons during late embryogenesis. This protein also plays a role in synapse organization between parallel fibers and Purkinje cells. Alternate splicing results in multiple transcript variants encoding distinct isoforms. Mutations in this gene cause cerebellar ataxia in humans.
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分子量
- 113kD
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基因ID
- 2895
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UniProt
- O43424
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途径
- Synaptic Membrane
抗原
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