Neurofibromin 1 抗体
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- 抗原 See all Neurofibromin 1 (NF1) 抗体
- Neurofibromin 1 (NF1)
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Neurofibromin 1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- This antibody detects endogenous levels of Neurofibromin protein.(region surrounding Arg1575)
- 纯化方法
- Affinity Chromatography using epitope-specific immunogen.
- Top Product
- Discover our top product NF1 Primary Antibody
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anti-Neurofibromin 1 (NF1) (pSer2741) antibody
NF1 适用: 人, 小鼠, 大鼠, Cow, 犬 ELISA, WB, IP, DB 宿主: 兔 Polyclonal unconjugated
anti-Neurofibromin 1 (NF1) (Internal Region) antibodyNF1 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Neurofibromin 1 (NF1) (AA 655-892) antibodyNF1 适用: 人 ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Neurofibromin 1 (NF1) antibodyNF1 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Neurofibromin 1 (NF1) (AA 1551-1600) antibodyNF1 适用: 人, 小鼠, 大鼠 ELISA, WB, IF, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Neurofibromin 1 (NF1) (AA 2719-2818) antibodyNF1 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 2D1 unconjugated
anti-Neurofibromin 1 (NF1) (C-Term) antibodyNF1 适用: 人, 小鼠, 大鼠, Cow, 犬 ELISA, WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Neurofibromin 1 (NF1) antibodyNF1 适用: 人, 小鼠, 大鼠 ELISA, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Neurofibromin 1 (NF1) (Center) antibodyNF1 适用: 人, 小鼠, 大鼠, 小鸡, 猴, Pig WB, IF, IHC, IC 宿主: 兔 Polyclonal unconjugated
anti-Neurofibromin 1 (NF1) (Internal Region) antibodyNF1 适用: 人, 小鼠, 大鼠 ELISA, WB, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1/20000-1/40000. Western Blot: 1/500-1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH ~7.2 containing 0.05 % Sodium Azide as preservative.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- Neurofibromin 1 (NF1)
- 别名
- Neurofibromin (NF1 产品)
- 别名
- NFNS antibody, VRNF antibody, WSS antibody, CG8318 antibody, Dmel\\CG8318 antibody, NF-1 antibody, NF1 antibody, Nf-1 antibody, dNF1 antibody, nf1 antibody, fe06d03 antibody, hm:zehn0874 antibody, wu:fe06d03 antibody, zehn0874 antibody, AW494271 antibody, E030030H24Rik antibody, neurofibromin 1 antibody, Neurofibromin 1 antibody, neurofibromin 1a antibody, neurofibromin antibody, putative neurofibromin antibody, NF1 antibody, Nf1 antibody, nf1a antibody, LOC593418 antibody, LOC5570549 antibody, CpipJ_CPIJ011774 antibody, Smp_148460 antibody
- 背景
- Neurofibromatosis type 1 (NF1), or von Reckinghausen neurofibromatosis, is one of the most common autosomal dominant disorders in humans. Early linkage analysis mapped the NF1 gene to chromosome 17. The predicted NF1 transcript encodes a 2818 amino acid protein designated NF1GRP. By sequence analysis, similarity has been demonstrated within a small region of NF1GRP and members of the Ras GAP gene family. Functionally, NF1GRP was shown by biochemical analysis involving RAS-GAP hydrolysis and functional complementation in yeast to further resemble GAP protein. The NF1 protein is expressed at relatively constant levels in a broad range of cell lines and tissues including brain, lung, liver, kidney, spleen, muscle and colon. Although little is known regarding the function of NF1GRP, the homology with the catalytic domain of proteins with GTPase activity suggests that the NF1GRP may also interact in vivo with Ras proteins.Synonyms: NF-1, NF1
- 分子量
- approx. 319 kDa
- 基因ID
- 4763
- NCBI登录号
- NP_000258
- UniProt
- P21359
- 途径
- cAMP Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity
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