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Neurofibromin 1 产品

(Neurofibromin 1 (NF1))
This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. [provided by RefSeq, Jul 2008].

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Featured Neurofibromin 1 Categories

Neurofibromin 1 抗体

High quality antibodies with extensive validation data.

Neurofibromin 1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

Neurofibromin 1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Neurofibromin 1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Cow, Dog, Human, Mouse, Rat
Application ELISA, WB, IP, DB
Validations
  • (1)
  • (2)
Cat. No. ABIN540944
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF, IHC (p), EIA
Validations
  • (4)
Cat. No. ABIN953662
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IF, IHC
Validations
  • (2)
Cat. No. ABIN7161270
Quantity 100 μg
Datasheet Datasheet

Recommended Neurofibromin 1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6968859
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1144677
Quantity 96 tests
Datasheet Datasheet
Reactivity Chicken
Analytical Method
Validations
Cat. No. ABIN1144674
Quantity 96 tests
Datasheet Datasheet

Recommended Neurofibromin 1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1312428
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124148
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3094141
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our Neurofibromin 1 Products

Miwa, Inoue, Sakamoto: "MRG-1 is required for both chromatin-based transcriptional silencing and genomic integrity of primordial germ cells in Caenorhabditis elegans." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 24, Issue 5, pp. 377-389, (2019) (PubMed).

Yoshioka, Gros, Li, Kumar, Deacon, Maron, Muotri, Chi, Fu, Yu, Dowdy: "Efficient generation of human iPSCs by a synthetic self-replicative RNA." in: Cell stem cell, Vol. 13, Issue 2, pp. 246-54, (2013) (PubMed).

Wallace, Pfefferle, Shen, McNairn, Cerami, Fallon, Rinaldi, Southard, Perou, Schimenti: "Comparative oncogenomics implicates the neurofibromin 1 gene (NF1) as a breast cancer driver." in: Genetics, Vol. 192, Issue 2, pp. 385-96, (2012) (PubMed).

Tucker, Riccardi, Brown, Fee, Sutcliffe, Vielkind, Wechsler, Wolkenstein, Friedman: "S100B and neurofibromin immunostaining and X-inactivation patterns of laser-microdissected cells indicate a multicellular origin of some NF1-associated neurofibromas." in: Journal of neuroscience research, Vol. 89, Issue 9, pp. 1451-60, (2011) (PubMed).

Kweh, Zheng, Kurenova, Wallace, Golubovskaya, Cance: "Neurofibromin physically interacts with the N-terminal domain of focal adhesion kinase." in: Molecular carcinogenesis, Vol. 48, Issue 11, pp. 1005-17, (2009) (PubMed).

Sales, Engelmayr, Johnson, Gao, Wang, Sacks, Mayer et al.: "Protein precoating of elastomeric tissue-engineering scaffolds increased cellularity, enhanced extracellular matrix protein production, and differentially regulated the phenotypes of circulating ..." in: Circulation, Vol. 116, Issue 11 Suppl, pp. I55-63, (2007) (PubMed).

Kuorilehto, Ekholm, Nissinen, Hietaniemi, Hiltunen, Paavolainen, Penttinen, Peltonen: "NF1 gene expression in mouse fracture healing and in experimental rat pseudarthrosis." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 54, Issue 3, pp. 363-70, (2006) (PubMed).

Hisaoka, Hashimoto, Ohguri, Aoki, Okamoto, Tanaka, Okimoto, Nakamura, Ishida: "Congenital (infantile) pseudarthrosis of the fibula associated with osteofibrous dysplasia." in: Skeletal radiology, Vol. 33, Issue 9, pp. 545-9, (2004) (PubMed).

Zou, Butcher, Sadikovic, Groves, Yee, Rodenhiser: "Characterization of functional elements in the neurofibromatosis (NF1) proximal promoter region." in: Oncogene, Vol. 23, Issue 2, pp. 330-9, (2004) (PubMed).

Zhu, Saberwal, Lu, Platanias, Eklund: "The interferon consensus sequence-binding protein activates transcription of the gene encoding neurofibromin 1." in: The Journal of biological chemistry, Vol. 279, Issue 49, pp. 50874-85, (2004) (PubMed).

Synonyms and alternative names related to Neurofibromin 1

neurofibromin 1 (NF1), neurofibromin 1 (Nf1), Neurofibromin 1 (Nf1), neurofibromin 1a (nf1a), neurofibromin (LOC593418), neurofibromin (LOC5570549), neurofibromin (CpipJ_CPIJ011774), putative neurofibromin (Smp_148460), AW494271, CG8318, Dmel\\CG8318, dNF1, E030030H24Rik, fe06d03, hm:zehn0874, NF-1, Nf-1, NF1, nf1, NFNS, VRNF, WSS, wu:fe06d03, zehn0874

Protein level used designations for Neurofibromin 1

  • neurofibromatosis-related protein NF-1
  • neurofibromin
  • Neurofibromatosis type 1
  • neurofibromatosis 1
  • CG8318-PB
  • CG8318-PC
  • CG8318-PD
  • CG8318-PE
  • CG8318-PF
  • Neurofibromatosis-1
  • Nf1-PB
  • Nf1-PC
  • Nf1-PD
  • Nf1-PE
  • Nf1-PF
  • neurofibramatosis-1
  • neurofibromatosis factor 1
  • neurofibromatosis type 1
  • neurofibromin 1
  • neurofibromin 1 (neurofibromatosis, von Recklinghausen disease, Watson disease)
  • neurofibromin-like
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