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LTBR 抗体 (Extracellular Domain) (PE)

LTBR 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal 5G11b PE
产品编号 ABIN317402
发货至: 中国
  • 抗原 See all LTBR 抗体
    LTBR (Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR))
    抗原表位
    • 15
    • 9
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    • 3
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    • 2
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    • 1
    • 1
    • 1
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    • 1
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    Extracellular Domain
    适用
    • 55
    • 50
    • 1
    小鼠
    宿主
    • 48
    • 17
    • 16
    大鼠
    克隆类型
    • 50
    • 29
    单克隆
    标记
    • 47
    • 7
    • 6
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LTBR antibody is conjugated to PE
    应用范围
    • 54
    • 34
    • 23
    • 13
    • 13
    • 10
    • 9
    • 7
    • 7
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    • 6
    • 4
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    Flow Cytometry (FACS)
    特异性
    This antibody recognises lymphotoxin-beta receptor (LT beta R), a member of the tumour necrosis factor family. LT beta R is primarily expressed on stromal cells and fibroblasts and at lower levels on myeloid cell lines. Clone 5G11b specifically recognises surface expressed LT beta R. The clone is reported to be agonistic with respect to NF Kappa B activation, MIP-2 induction and IL-6 release (2). This product is routinely tested on mouse WEHI cells.
    产品特性
    Synonyms: Tumor necrosis factor receptor 3, TNF-R3, Tumor necrosis factor C receptor, TNFCR,TNFRSF3, D12S370, Lymphotoxin-beta receptor, Tumor necrosis factor receptor superfamilymember 3, Tumor necrosis factor receptor type III, Tumor necrosis factor receptor 2-relatedprotein
    纯化方法
    Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
    免疫原
    Recombinant extracellular domain of LT beta R
    克隆位点
    5G11b
    亚型
    IgG2a
    Top Product
    Discover our top product LTBR Primary Antibody
  • 应用备注
    Flow Cytometry: use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 溶解方式
    Reconstitute with 1.0 mL distilled water
    浓度
    0.05 mg/mL
    缓冲液
    Phosphate buffered saline pH 7.4, 0.09 % Sodium Azide, 1 % Bovine Serum Albumin
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody prior and following reconstitution at 2-8 °C. DO NOT FREEZE. This product is photosensitive and should be protected from light.
    Shelf life: One year from despatch.
    有效期
    12 months
  • 抗原
    LTBR (Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR))
    别名
    LTBR / TNFR3 (LTBR 产品)
    别名
    AI256028 antibody, CD18 antibody, LTbetaR antibody, Ltar antibody, TNF-R-III antibody, TNFCR antibody, TNFR-RP antibody, TNFR2-RP antibody, TNFRrp antibody, Tnfbr antibody, Tnfrsf3 antibody, D12S370 antibody, LT-BETA-R antibody, TNFR3 antibody, TNFRSF3 antibody, lymphotoxin beta receptor antibody, lymphotoxin B receptor antibody, Ltbr antibody, LTBR antibody
    背景
    The protein encoded by this gene is a member of the tumor necrosis factor (TNF) family of receptors. It is expressed on the surface of most cell types, including cells of epithelial and myeloid lineages, but not on T and B lymphocytes. The protein specifically binds the lymphotoxin membrane form (a complex of lymphotoxin alpha and lymphtoxin beta). The encoded protein and its ligand play a role in the development and organization of lymphoid tissue and tranformed cells. Activation of the encoded protein can trigger apoptosis.Synonyms: D12S370, Lymphotoxin-beta receptor, TNF-R3, TNFCR, TNFRSF3, Tumor necrosis factor C receptor, Tumor necrosis factor receptor 2-related protein, Tumor necrosis factor receptor 3, Tumor necrosis factor receptor superfamily member 3, Tumor necrosis factor receptor type III
    基因ID
    4055
    UniProt
    P36941
    途径
    NF-kappaB Signaling
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