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IL-4 抗体

IL4 适用: 犬, Cow, Pig, 绵羊, Mustelid, 山羊 EIA 宿主: 小鼠 Monoclonal CC303 unconjugated
产品编号 ABIN317377
发货至: 中国
  • 抗原 See all IL-4 (IL4) 抗体
    IL-4 (IL4) (Interleukin 4 (IL4))
    适用
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    犬, Cow, Pig, 绵羊, Mustelid, 山羊
    宿主
    • 108
    • 58
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    小鼠
    克隆类型
    • 122
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    单克隆
    标记
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    This IL-4 antibody is un-conjugated
    应用范围
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    Enzyme Immunoassay (EIA)
    特异性
    This antibody recognises bovine interleukin 4.
    产品特性
    Synonyms: IL-4, BSF1, Lymphocyte stimulatory factor 1, Binetrakin, Pitrakinra, B-cell stimulatory factor1
    纯化方法
    Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
    克隆位点
    CC303
    亚型
    IgG2a
    Top Product
    Discover our top product IL4 Primary Antibody
  • 应用备注
    ELISA. Flow Cytometry: 1/50 - 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0mg/mL
    缓冲液
    Phosphate buffered saline pH 7.4 containing 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch. Caution: (A full Health and Safety assessment is available upon request) This product containssodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled bytrained staff only.
    有效期
    12 months
  • 抗原
    IL-4 (IL4) (Interleukin 4 (IL4))
    别名
    Interleukin-4 / IL4 (IL4 产品)
    别名
    IL4 antibody, IL-4 antibody, BCGF-1 antibody, BCGF1 antibody, BSF-1 antibody, BSF1 antibody, Il-4 antibody, Il4e12 antibody, IL2 antibody, interleukin 4 antibody, IL4 antibody, Il4 antibody
    背景
    IL4 is a pleiotropic cytokine produced by activated T cells, mast cells and basophils. It is a ligand for Interleukin 4 receptor. The Interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. IL4 elicits many different biological responses, but has two dominant functions. The first is regulating differentiation of naive CD4+ T cell to the Th2 type. Th2 cells produce IL4, IL5, IL10 and IL13, which tend to favor a humoral immune response while suppressing a cell mediated immune response controlled by Th1 cells. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. The second is regulating IgE and IgG1 production by B cells. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.Synonyms: B-cell stimulatory factor 1, BSF1, Binetrakin, IL-4, Lymphocyte stimulatory factor 1, Pitrakinra
    基因ID
    3565
    UniProt
    P05112
    途径
    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation
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