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CD74 抗体 (FITC)

CD74 适用: 人 FACS 宿主: 小鼠 Monoclonal Bu45 FITC
产品编号 ABIN316495
发货至: 中国
  • 抗原 See all CD74 抗体
    CD74 (HLA-DR-gamma (CD74))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CD74 antibody is conjugated to FITC
    应用范围
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    Flow Cytometry (FACS)
    特异性
    This antibody recognises CD74, a type II transmembrane protein, which is also known as the MHC class II associated invariant chain. The Bu45 antibody recognises 33, 35 and 41 kDa isoforms of CD74. The Bu45 antibody binds to an epitope within the extracytoplasmic domain of the CD74 Molecule, which is distal from the C-terminus. *Membrane permeabilisation may enhance CD74 staining on monocytes but is not required when staining lymphocytes.
    产品特性
    Synonyms: p33, DHLAG, HLA class II histocompatibility antigen gamma chain, HLA-DRantigens-associated invariant chain, Ia antigen-associated invariant chain
    纯化方法
    Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
    免疫原
    B lymphoblastoid cell line HFB1.
    克隆位点
    Bu45
    亚型
    IgG1
    Top Product
    Discover our top product CD74 Primary Antibody
  • 应用备注
    Flow Cytometry: 1/5, 10l of the suggested working dilution to label 1x10^6 cells in 100 μL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.1mg/mL
    缓冲液
    Phosphate buffered saline pH 7.4 containing 0.09 % Sodium Azide (NaN3), 1 % Bovine Serum Albumin
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.
    Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    CD74 (HLA-DR-gamma (CD74))
    别名
    CD74 (CD74 产品)
    别名
    DHLAG antibody, HLADG antibody, II antibody, Ia-GAMMA antibody, CLIP antibody, Ii antibody, INVG34 antibody, Iclp-1 antibody, iclp1 antibody, wu:fb11f09 antibody, wu:fb12a01 antibody, wu:fb13d06 antibody, wu:fk94e07 antibody, Iclp-2 antibody, cd74 antibody, iclp2 antibody, zgc:123161 antibody, CD74 molecule antibody, CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) antibody, CD74 molecule, major histocompatibility complex, class II invariant chain a antibody, CD74 molecule, major histocompatibility complex, class II invariant chain b antibody, CD74 antibody, Cd74 antibody, cd74a antibody, cd74b antibody
    背景
    The CD74 Molecule plays a critical role in the presentation of peptides, by the MHC class II antigens, to CD4 positive lymphocytes. CD74 is expressed on MHC class II positive cells including B cells, a subset of activated T cells, monocytes, dendritic cells and by various types of carcinoma. Expression of CD74 is primarily intracellular with moderate expression at the cell surface of B cells and monocytes.Synonyms: DHLAG, HLA class II histocompatibility antigen gamma chain, HLA-DR antigens-associated invariant chain, Ia antigen-associated invariant chain, p33
    基因ID
    972
    UniProt
    P04233
    途径
    Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Negative Regulation of intrinsic apoptotic Signaling, Cancer Immune Checkpoints
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