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Insulin 抗体 (full length)

This 小鼠 单克隆 antibody specifically detects Insulin in IHC, WB 和 ELISA. It exhibits reactivity toward 人, Pig 和 Cow.
产品编号 ABIN307024
发货至: 中国
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Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Insulin 抗体 (full length) (ABIN307024)

抗原

See all Insulin (INS) 抗体
Insulin (INS)

适用

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人, Pig, Cow

宿主

  • 180
  • 134
  • 12
  • 1
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小鼠

克隆类型

  • 209
  • 121
  • 1
单克隆

标记

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This Insulin antibody is un-conjugated

应用范围

  • 128
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Immunohistochemistry (IHC), Western Blotting (WB), ELISA

克隆位点

E2E3
  • 抗原表位

    • 16
    • 10
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    full length

    原理

    Mouse anti Human Insulin

    交叉反应

    Cow, 人, Pig

    产品特性

    Insulin is one of the major regulatory hormones of intermediate metabolism throughout the body. The biological actions of this hormone involve integration of carbohydrate, protein, and lipid metabolism. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides and synthesis of proteins and nucleic acids. Immunocytochemical investigations have localized insulin in the B cells of pancreatic islets of Langerhans. Deficiency of insulin results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population. Insulin is also present in tumors of B cell origin such as insulinoma.

    纯化方法

    Protein A/G Chromatography

    免疫原

    Hybridoma produced by the fusion of splenocytes from mice immunized with full-length insulin protein and mouse myeloma cells.

    亚型

    IgG1
  • 应用备注

    Antibody can be used for Western blotting (1-5 μg/mL), immunohistochemistry on formalin-fixed, paraffin-embedded tissues (1-2 μg/mL, incubate at room temp. for at least 1 hr.) and ELISA. Optimal concentration should be evaluated by serial dilutions.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    phosphate buffered saline with 0.08 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
  • 抗原

    Insulin (INS)

    别名

    Insulin

    UniProt

    P01308

    途径

    NF-kappaB Signaling, RTK signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagy, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
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