Caspase 9 抗体
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北京 101111
Quick Overview for Caspase 9 抗体 (ABIN306797)
抗原
See all Caspase 9 (CASP9) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Mouse anti Human Caspase-9
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交叉反应
- 人
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产品特性
- Caspases are key effectors of programmed cell death. They are synthesized as inactive proenzymes which are activated by cleavage at a specific aspartate residue to form two subunits. These subunits are normally linked together by a linker which may be involved in the regulation of the different caspases. Caspase-9 is a member of the CED-3 family and bear high similarity to caspase-3. Procaspase-9 can be activated by either caspase-3 or granzyme B, although they cleave the proenzyme to different size subunits. Cleavage by granzyme B produces an active enzyme which is capable of cleaving PARP. Also, the ability of caspase-3 to activate caspase-9 seems to suggest that caspase-9 is further downstream of caspase-3 and may be involved in later changes in cells observed undergoing apoptosis.
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纯化方法
- Protein A/G Chromatography
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免疫原
- Hybridoma produced by the fusion of splenocytes from mice immunized with recombinant human capase-9 protein and mouse myeloma cells.
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亚型
- IgG
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anti-Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9) (AA 1-98) antibody
CASP9 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9) (AA 11-120) antibodyCASP9 适用: 人, 小鼠, 大鼠, 小鸡, 兔, 犬 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9) (AA 331-416) antibodyCASP9 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9) antibodyCASP9 适用: 人, 小鼠, 大鼠, 小鸡 WB, IHC, IF, IP 宿主: 小鼠 Monoclonal unconjugated
anti-Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9) (AA 331-416) antibodyCASP9 适用: 人 WB, FACS 宿主: 兔 Polyclonal unconjugated
anti-Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9) (AA 1-200) antibodyCASP9 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9) (AA 1-200) antibodyCASP9 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9) (AA 1-416) antibodyCASP9 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 3B8-4G2 unconjugated
anti-Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9) antibodyKD Validated CASP9 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB1005 unconjugated Recombinant Antibody
anti-Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9) (AA 271-314) antibodyCASP9 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Detects proenzyme form of human Caspase-9 by Western blot analysis as well as one of the cleavage products after treatment with thapsigargin. Optimal concentration should be evaluated by serial dilutions.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- phosphate buffered saline with 0.08 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- Caspase 9 (CASP9) (Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9))
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别名
- Caspase-9
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背景
- Cysteine-requiring Aspartate Protease-9, iCE-like apoptotic protease 6,Apoptotic protease Mch-6, Apoptotic protease-activating factor 3
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UniProt
- P55211
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途径
- MAPK Pathway, RTK signaling, Apoptosis, Caspase Cascade in Apoptosis, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Endopeptidase Activity
抗原
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