BCAR3 抗体 (C-Term)
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- 抗原 See all BCAR3 抗体
- BCAR3 (Breast Cancer Anti-Estrogen Resistance 3 (BCAR3))
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抗原表位
- AA 791-825, C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BCAR3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for Breast cancer anti-estrogen resistance protein 3(BCAR3) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
- 序列
- KGAQVNQTER YEKFNQILTA LSRKLEPPPV KQAEL
- 交叉反应 (详细)
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Breast cancer anti-estrogen resistance protein 3(BCAR3) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: breast cancer anti-estrogen resistance 3
Protein Name: Breast cancer anti-estrogen resistance protein 3 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human BCAR3 (791-825aa KGAQVNQTERYEKFNQILTALSRKLEPPPVKQAEL), different from the related mouse sequence by five amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product BCAR3 Primary Antibody
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- BCAR3 (Breast Cancer Anti-Estrogen Resistance 3 (BCAR3))
- 别名
- BCAR3 (BCAR3 产品)
- 别名
- NSP2 antibody, SH2D3B antibody, AI131758 antibody, AND-34 antibody, BCAR3 antibody, breast cancer anti-estrogen resistance 3 antibody, breast cancer anti-estrogen resistance 3 L homeolog antibody, BCAR3 antibody, Bcar3 antibody, bcar3 antibody, bcar3.L antibody
- 背景
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Breast cancer anti-estrogen resistance protein 3 is a protein that in humans is encoded by the BCAR3 gene. Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estrogen resistant. Breast cancer anti-estrogen resistance gene 3 was identified in the search for genes involved in the development of estrogen resistance. The gene encodes a component of intracellular signal transduction that causes estrogen-independent proliferation in human breast cancer cells. The protein contains a putative src homology 2 (SH2) domain, a hall mark of cellular tyrosine kinase signaling molecules, and is partly homologous to the cell division cycle protein CDC48. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms: BCAR 3 antibody|BCAR3 antibody|BCAR3_HUMAN antibody|Breast cancer anti estrogen resistance 3 antibody|Breast cancer anti estrogen resistance protein 3 antibody|Breast cancer anti-estrogen resistance protein 3 antibody|Breast cancer antiestrogen resistance 3 antibody|dJ1033H22.2 antibody|dJ1033H22.2 breast cancer anti estrogen resistance 3 antibody|dJ1033H22.2 breast cancer antiestrogen resistance 3 antibody|KIAA0554 antibody|Novel SH2 containing protein 2 antibody|Novel SH2-containing protein 2 antibody|NSP 2 antibody|NSP2 antibody|SH2 containing protein Nsp2 antibody|SH2 domain containing protein 3B antibody|SH2 domain-containing protein 3B antibody|SH2D3B antibody - 基因ID
- 8412
- UniProt
- O75815
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