电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

BCAR3 抗体 (AA 761-810)

This 兔 多克隆 antibody specifically detects BCAR3 in WB, IHC, ELISA 和 IF. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN1533543
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for BCAR3 抗体 (AA 761-810) (ABIN1533543)

抗原

See all BCAR3 抗体
BCAR3 (Breast Cancer Anti-Estrogen Resistance 3 (BCAR3))

适用

  • 25
  • 19
  • 16
  • 1
人, 小鼠, 大鼠

宿主

  • 25
  • 2
  • 1
兔

克隆类型

  • 26
  • 2
多克隆

标记

  • 18
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This BCAR3 antibody is un-conjugated

应用范围

  • 26
  • 20
  • 8
  • 6
  • 5
  • 4
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 17
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 761-810

    原理

    BCAR3 Antibody

    特异性

    BCAR3 Polyclonal Antibody detects endogenous levels of BCAR3 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human BCAR3. AA range:761-810

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    BCAR3 (Breast Cancer Anti-Estrogen Resistance 3 (BCAR3))

    别名

    BCAR3

    背景

    Synonyms: BCAR3, NSP2, SH2D3B, Breast cancer anti-estrogen resistance protein 3, Novel SH2-containing protein 2, SH2 domain-containing protein 3B

    Background: breast cancer anti-estrogen resistance 3(BCAR3) Homo sapiens Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estrogen resistant. Breast cancer anti-estrogen resistance gene 3 was identified in the search for genes involved in the development of estrogen resistance. The gene encodes a component of intracellular signal transduction that causes estrogen-independent proliferation in human breast cancer cells. The protein contains a putative src homology 2 (SH2) domain, a hall mark of cellular tyrosine kinase signaling molecules, and is partly homologous to the cell division cycle protein CDC48. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012],

    Gene Name: BCAR3

    Protein Name: Breast cancer anti-estrogen resistance protein 3

    分子量

    92 kDa

    基因ID

    8412

    OMIM

    604704

    UniProt

    O75815
You are here: