BCAR3 抗体 (AA 730-810)
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北京 101111
Quick Overview for BCAR3 抗体 (AA 730-810) (ABIN7225364)
抗原
See all BCAR3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 730-810
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原理
- Rabbit Anti-BCAR3 Polyclonal Antibody
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特异性
- BCAR3 Polyclonal Antibody detects endogenous levels of BCAR3 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from the C-terminal region of human BCAR3 at AA range: 730-810
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亚型
- IgG
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anti-Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) (C-Term) antibody
BCAR3 适用: 人, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) (C-Term) antibodyBCAR3 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) (AA 266-373) antibodyBCAR3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3G4 unconjugated
anti-Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) (C-Term) antibodyBCAR3 适用: 人, Cow WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) (AA 785-818), (C-Term) antibodyBCAR3 适用: 小鼠 WB 宿主: 兔 Polyclonal RB43280 unconjugated
anti-Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) (C-Term) antibodyVerified BCAR3 适用: 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) (AA 548-818) antibodyBCAR3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) (AA 761-810) antibodyBCAR3 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:10000,Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- BCAR3 (Breast Cancer Anti-Estrogen Resistance 3 (BCAR3))
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别名
- BCAR3
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背景
- BCAR3, NSP2, SH2D3B, Breast cancer anti-estrogen resistance protein 3, Novel SH2-containing protein 2, SH2 domain-containing protein 3BBreast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estrogen resistant. Breast cancer anti-estrogen resistance gene 3 was identified in the search for genes involved in the development of estrogen resistance. BCAR3 (breast cancer anti-estrogen resistance 3) encodes a component of intracellular signal transduction that causes estrogen-independent proliferation in human breast cancer cells. The protein contains a putative src homology 2 (SH2) domain, a hall mark of cellular tyrosine kinase signaling molecules, and is partly homologous to the cell division cycle protein CDC48. Multiple transcript variants encoding different isoforms have been found for BCAR3.
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分子量
- 92kD
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基因ID
- 8412
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UniProt
- O75815
抗原
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