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PLAUR 抗体 (C-Term)

PLAUR 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3044378
发货至: 中国
  • 抗原 See all PLAUR 抗体
    PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))
    抗原表位
    • 16
    • 7
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 293-304, C-Term
    适用
    • 61
    • 28
    • 27
    宿主
    • 55
    • 15
    • 4
    • 3
    克隆类型
    • 62
    • 15
    多克隆
    标记
    • 41
    • 8
    • 8
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PLAUR antibody is un-conjugated
    应用范围
    • 60
    • 28
    • 24
    • 20
    • 13
    • 12
    • 12
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for Urokinase plasminogen activator surface receptor(PLAUR) detection. Tested with WB, IHC-P in Human.
    序列
    CNHPDLDVQY RS
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Urokinase plasminogen activator surface receptor(PLAUR) detection. Tested with WB, IHC-P in Human.
    Gene Name: plasminogen activator, urokinase receptor
    Protein Name: Urokinase plasminogen activator surface receptor(U-PAR/uPAR)
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the C-terminus of human uPA Receptor(293-304aa CNHPDLDVQYRS).
    亚型
    IgG
    Top Product
    Discover our top product PLAUR Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    有效期
    12 months
  • 抗原
    PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))
    别名
    PLAUR (PLAUR 产品)
    别名
    Cd87 antibody, u-PAR antibody, uPAR antibody, CD87 antibody, U-PAR antibody, UPAR antibody, URKR antibody, Par antibody, Plaur3 antibody, uPAR-2 antibody, uPAR-3 antibody, PLAUR antibody, plasminogen activator, urokinase receptor antibody, Plaur antibody, PLAUR antibody
    背景
    PLAUR(PLASMINOGEN ACTIVATOR RECEPTOR, UROKINASE-TYPE), also known as UPAR or CD87, is multidomain glycoprotein tethered to the cell membrane with a glycosylphosphotidylinositol(GPI) anchor. PLAUR consists of three different domains of the Ly-6/uPAR/alpha-neurotoxin family. PLAUR is originally identified as a saturable binding site for urokinase on the cell surface. And the gene plays an important role in many normal as well as pathologic processes. The PLAUR gene is localized to 19q13.31. PLAUR is a part of the plasminogen activation system, which in the healthy body is involved in tissue reorganization events such as mammary gland involution and wound healing. PLAUR binds urokinase and thus restricts plasminogen activation to the immediate vicinity of the cell membrane. Thus it seems to be an important player in the regulation of this process. In human coronary artery vascular smooth muscle cells, UPA stimulates cell migration via a UPAR signaling complex containing TYK2 and phosphatidylinositol 3-kinase.

    Synonyms: CD 87 antibody|CD87 antibody|CD87 antigen antibody|MO 3 antibody|MO3 antibody|Monocyte activation antigen Mo3 antibody|Plasminogen activator urokinase receptor antibody|PLAUR antibody|U PAR antibody|u plasminogen activator receptor antibody|U-PAR antibody|UPA receptor antibody|UPAR antibody|UPAR_HUMAN antibody|Urinary plasminogen activator receptor antibody|URKR antibody|Urokinase plasminogen activator receptor antibody|Urokinase plasminogen activator surface receptor antibody
    UniProt
    Q03405
    途径
    Inositol Metabolic Process
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