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PLAUR 抗体

KO Validated PLAUR 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2854760
发货至: 中国
  • 抗原 See all PLAUR 抗体
    PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))
    适用
    • 60
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    宿主
    • 54
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    克隆类型
    • 61
    • 15
    多克隆
    标记
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    This PLAUR antibody is un-conjugated
    应用范围
    • 59
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    Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    产品特性
    Rabbit Polyclonal antibody to uPAR (plasminogen activator, urokinase receptor)
    uPAR antibody
    纯化方法
    Purified by antigen-affinity chromatography.
    质量等级
    KO Validated
    免疫原
    Recombinant protein encompassing a sequence within the center region of human uPAR. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product PLAUR Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: U87-MG , HeLa

    Validation: Comparison, KO/KD

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.34 mg/mL
    缓冲液
    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))
    别名
    plasminogen activator, urokinase receptor (PLAUR 产品)
    别名
    Cd87 antibody, u-PAR antibody, uPAR antibody, CD87 antibody, U-PAR antibody, UPAR antibody, URKR antibody, Par antibody, Plaur3 antibody, uPAR-2 antibody, uPAR-3 antibody, PLAUR antibody, plasminogen activator, urokinase receptor antibody, Plaur antibody, PLAUR antibody
    背景
    This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined.

    Cellular Localization: Isoform 1: Cell membrane, Lipid-anchor , GPI-anchor , Isoform 2: Secreted
    分子量
    37 kDa
    基因ID
    5329
    UniProt
    Q03405
    途径
    Inositol Metabolic Process
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