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VEGFD 抗体 (Middle Region)

Figf 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3044291
发货至: 中国
  • 抗原 See all VEGFD (Figf) 抗体
    VEGFD (Figf) (C-Fos Induced Growth Factor (Vascular Endothelial Growth Factor D) (Figf))
    抗原表位
    • 14
    • 10
    • 9
    • 8
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 101-115, Middle Region
    适用
    • 62
    • 21
    • 15
    • 2
    • 1
    • 1
    人, 大鼠
    宿主
    • 51
    • 16
    • 1
    克隆类型
    • 51
    • 17
    多克隆
    标记
    • 39
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This VEGFD antibody is un-conjugated
    应用范围
    • 53
    • 30
    • 25
    • 11
    • 11
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for Vascular endothelial growth factor D(FIGF) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    序列
    VIDEEWQRTQ CSPRE
    交叉反应 (详细)
    Predicted Cross Reactivity: mouse
    No cross reactivity with other proteins.
    Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
    产品特性
    Rabbit IgG polyclonal antibody for Vascular endothelial growth factor D(FIGF) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Gene Name: c-fos induced growth factor(vascular endothelial growth factor D)(VEGF-D)
    Protein Name: Vascular endothelial growth factor D
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence in the middle region of human VEGFD(101-115aa VIDEEWQRTQCSPRE), identical to the related rat and mouse sequences.
    亚型
    IgG
    Top Product
    Discover our top product Figf Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    有效期
    12 months
  • Qi, Du, Chen, Chen, Yi, Chen, Wen, Wei, Zhao: "VEGF-D-enhanced lymph node metastasis of ovarian cancer is reversed by vesicular stomatitis virus matrix protein." in: International journal of oncology, Vol. 49, Issue 1, pp. 123-32, (2017) (PubMed).

  • 抗原
    VEGFD (Figf) (C-Fos Induced Growth Factor (Vascular Endothelial Growth Factor D) (Figf))
    别名
    VEGF-D (Figf 产品)
    别名
    FIGF antibody, vegfd antibody, vegf-d antibody, VEGFD antibody, AI325264 antibody, VEGF-D antibody, Vegfd antibody, Vegf-d antibody, vascular endothelial growth factor D antibody, Vascular endothelial growth factor D antibody, VEGFD antibody, vegfd antibody, vegfd.L antibody, Vegfd antibody
    背景
    C-fos induced growth factor(FIGF)(or vascular endothelial growth factor D, VEGF-D) is a vascular endothelial growth factor that in humans is encoded by the FIGF gene. The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor(PDGF/VEGF) family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. Analyzing by Northern blotting, Yamada et al.(1997) symbolized VEGFD, was expressed as a 2.2-kb transcript with highest expression in lung, heart, small intestine, and fetal lung, and lower levels in skeletal muscle, colon, and pancreas. And Achen et al.(1998) concluded that VEGFD was most closely related to VEGFC by virtue of the presence of N- and C-terminal extensions that were not found in other VEGF family members. Stacker et al.(2001) showed that VEGFD can induce tumor angiogenesis through VEGFR2 and tumor lymphangiogenesis through VEGFR3, whereas VEGF, which does not activate VEGFR3, induces only tumor angiogenesis.

    Synonyms: c-fos induced growth factor antibody|c-fos induced growth factor(vascular endothelial growth factor D) antibody|c-fos-induced growth factor antibody|FIGF antibody|Vascular endothelial growth factor D antibody|Vascular endothelial growth factor D precursor antibody|VEGF D antibody|VEGF-D antibody|VEGFD antibody|VEGFD_HUMAN antibody
    UniProt
    O43915
    途径
    RTK signaling
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