Dual Specificity Phosphatase 3 (DUSP3) (AA 155-171), (C-Term) 抗体
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- 抗原 See all Dual Specificity Phosphatase 3 (DUSP3) 抗体
- Dual Specificity Phosphatase 3 (DUSP3)
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抗原表位
- AA 155-171, C-Term
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- 非结合性
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应用范围
- Western Blotting (WB)
- 原理
- Rabbit IgG polyclonal antibody for Dual specificity protein phosphatase 3(DUSP3) detection. Tested with WB in Human,Mouse,Rat.
- 序列
- RQNREIGPND GFLAQLC
- 交叉反应 (详细)
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Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities. - 产品特性
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Rabbit IgG polyclonal antibody for Dual specificity protein phosphatase 3(DUSP3) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: dual specificity phosphatase 3
Protein Name: Dual specificity protein phosphatase 3 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human DUSP3(155-171aa RQNREIGPNDGFLAQLC), identical to the related rat and mouse sequences.
- 亚型
- IgG
- Top Product
- Discover our top product DUSP3 Primary Antibody
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Thimerosal (Merthiolate), Sodium azide
- 注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - 有效期
- 12 months
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- 抗原
- Dual Specificity Phosphatase 3 (DUSP3)
- 别名
- DUSP3 (DUSP3 产品)
- 别名
- dusp3 antibody, si:bz18k17.3 antibody, si:rp71-18k17.3 antibody, VHR antibody, RGD1560049 antibody, 2210015O03Rik antibody, 5031436O03Rik antibody, T-DSP11 antibody, dual specificity phosphatase 3 antibody, dual specificity phosphatase 3b antibody, dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related) antibody, DUSP3 antibody, dusp3b antibody, Dusp3 antibody
- 物质类
- Viral Protein
- 背景
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DUSP3(Dual-specificity phosphatase 3), also called VHR, is a member of the dual specificity protein phosphatase subfamily. DUSPs constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. DUSP3 contains the consensus DUSP C-terminal catalytic domain but lacks the N-terminal CH2 domain found in the MKP(mitogen-activated protein kinase phosphatase) class of DUSPs. The DUSP3 gene is mapped on 17q21.31. Confocal microscopy demonstrated that phosphorylated VHR accumulated at the immune synapse between the T cell and the antigen-presenting cell in the presence of antigen. Tyrosine phosphorylation of VHR affects protein-protein interaction, subcellular location, or substrate targeting, given that tyr138 is located on the opposite side of the VHR catalytic center.
Synonyms: Dual specificity phosphatase 3 antibody|Dual specificity protein phosphatase 3 antibody|Dual specificity protein phosphatase VHR antibody|DUS3_HUMAN antibody|DUSP3 antibody|Serine/threonine specific protein phosphatase antibody|Vaccinia H1-related phosphatase antibody|Vaccinia virus phosphatase VH1 related antibody|VHR antibody - UniProt
- P51452
- 途径
- Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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