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Dual Specificity Phosphatase 3 (DUSP3) (AA 1-30), (N-Term) 抗体

DUSP3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB06032 unconjugated
产品编号 ABIN392924
发货至: 中国
  • 抗原 See all Dual Specificity Phosphatase 3 (DUSP3) 抗体
    Dual Specificity Phosphatase 3 (DUSP3)
    抗原表位
    • 15
    • 8
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-30, N-Term
    适用
    • 40
    • 21
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 51
    • 7
    克隆类型
    • 51
    • 7
    多克隆
    标记
    • 26
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    非结合性
    应用范围
    • 40
    • 23
    • 14
    • 13
    • 13
    • 12
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    预测反应
    M
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This DUSP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human DUSP3.
    克隆位点
    RB06032
    亚型
    Ig Fraction
    Top Product
    Discover our top product DUSP3 Primary Antibody
  • 应用备注
    WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Wang, Yeh, Chou, Yang, Fu, Chen, Cheng, Huang, Liu, Huang, Chen: "Vaccinia H1-related phosphatase is a phosphatase of ErbB receptors and is down-regulated in non-small cell lung cancer." in: The Journal of biological chemistry, Vol. 286, Issue 12, pp. 10177-84, (2011) (PubMed).

  • 抗原
    Dual Specificity Phosphatase 3 (DUSP3)
    别名
    DUSP3 (DUSP3 产品)
    别名
    dusp3 antibody, si:bz18k17.3 antibody, si:rp71-18k17.3 antibody, VHR antibody, RGD1560049 antibody, 2210015O03Rik antibody, 5031436O03Rik antibody, T-DSP11 antibody, dual specificity phosphatase 3 antibody, dual specificity phosphatase 3b antibody, dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related) antibody, DUSP3 antibody, dusp3b antibody, Dusp3 antibody
    物质类
    Viral Protein
    背景
    DUSP3 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli.
    分子量
    20478
    基因ID
    1845
    NCBI登录号
    NP_004081
    UniProt
    P51452
    途径
    Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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