电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

MALT1 抗体 (C-Term)

MALT1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3044126
发货至: 中国
  • 抗原 See all MALT1 抗体
    MALT1 (Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1))
    抗原表位
    • 20
    • 15
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 809-824, C-Term
    适用
    • 64
    • 18
    • 14
    • 1
    宿主
    • 42
    • 23
    • 1
    克隆类型
    • 43
    • 23
    多克隆
    标记
    • 38
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MALT1 antibody is un-conjugated
    应用范围
    • 53
    • 23
    • 17
    • 13
    • 13
    • 13
    • 12
    • 8
    • 8
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB)
    原理
    Rabbit IgG polyclonal antibody for Mucosa-associated lymphoid tissue lymphoma translocation protein 1(MALT1) detection. Tested with WB in Human.
    序列
    DEIPFSFSDR LRISEK
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Mucosa-associated lymphoid tissue lymphoma translocation protein 1(MALT1) detection. Tested with WB in Human.
    Gene Name: mucosa associated lymphoid tissue lymphoma translocation gene 1
    Protein Name: Mucosa-associated lymphoid tissue lymphoma translocation protein 1
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the C-terminus of human MALT1(809-824aa DEIPFSFSDRLRISEK).
    亚型
    IgG
    Top Product
    Discover our top product MALT1 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for MALT1 is approximately 0.5 ng/lane under reducing conditions.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    有效期
    12 months
  • 抗原
    MALT1 (Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1))
    别名
    MALT1 (MALT1 产品)
    别名
    malt1 antibody, MALT1 antibody, mlt antibody, mlt1 antibody, MLT antibody, MLT1 antibody, A630046N12 antibody, D430033E09Rik antibody, MALT paracaspase 2 antibody, MALT1 paracaspase antibody, MALT1 paracaspase S homeolog antibody, paracaspase 3 antibody, malt2 antibody, MALT1 antibody, malt1.S antibody, Malt1 antibody, PCASP3 antibody
    背景
    MALT1(Mucosa-associated lymphoid tissue lymphoma translocation protein 1), also called MLT or PARACASPASE, is a protein that in humans is encoded by the MALT1 gene. This gene has been found to be recurrently rearranged in chromosomal translocation with two other genes - baculoviral IAP repeat-containing protein 3(also known as apoptosis inhibitor 2) and immunoglobulin heavy chain locus - in mucosa-associated lymphoid tissue lymphomas. Dierlamm et al.(1999) and Akagi et al.(1999) mapped the MALT1 gene to chromosome 18q21. Using mouse models, Ruland et al.(2003) demonstrated that MALT1 is essential for T-cell activation, proliferation, and IL2 production in response to T-cell receptor ligation and strictly required for signal-specific NF-kappa-B(NFKB) activation induced by the T-cell receptor but not TNF-alpha or IL1 signaling. MALT1 operates downstream of BCL10, controls the catalytic activity of the canonical I-kappa-B kinase complex, and regulates the signaling of JNK and p38 MAP kinases.

    Synonyms: Caspase like protein antibody|DKFZp434L132 antibody|MALT 1 antibody|MALT associated translocation antibody|MALT lymphoma associated translocation antibody|MALT lymphoma-associated translocation antibody|Malt1 antibody|MALT1_HUMAN antibody|MLT 1 antibody|MLT antibody|MLT1 antibody|Mucosa associated lymphoid tissue lymphoma translocation gene 1 antibody|Mucosa associated lymphoid tissue lymphoma translocation protein 1 antibody|Mucosa-associated lymphoid tissue lymphoma translocation protein 1 antibody|Paracaspase antibody
    途径
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins
You are here:
客服