电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

CSF3R 抗体 (Middle Region)

CSF3R 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3044116
发货至: 中国
  • 抗原 See all CSF3R 抗体
    CSF3R (Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R))
    抗原表位
    • 12
    • 7
    • 7
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 254-271, Middle Region
    适用
    • 67
    • 25
    • 22
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 54
    • 14
    • 2
    • 1
    • 1
    克隆类型
    • 58
    • 14
    多克隆
    标记
    • 34
    • 7
    • 6
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CSF3R antibody is un-conjugated
    应用范围
    • 61
    • 30
    • 19
    • 17
    • 9
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB)
    原理
    Rabbit IgG polyclonal antibody for Granulocyte colony-stimulating factor receptor(CSF3R) detection. Tested with WB in Human.
    序列
    EPWQPGLHIN QKCELRHK
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Granulocyte colony-stimulating factor receptor(CSF3R) detection. Tested with WB in Human.
    Gene Name: Colony stimulating factor 3 receptor(granulocyte)
    Protein Name: Granulocyte colony-stimulating factor receptor
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence in the middle region of human GCSF Receptor(254-271aa EPWQPGLHINQKCELRHK).
    亚型
    IgG
    Top Product
    Discover our top product CSF3R Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for CSF3R is approximately 5 ng/lane under reducing conditions.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    有效期
    12 months
  • 抗原
    CSF3R (Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R))
    别名
    CSF3R (CSF3R 产品)
    别名
    CD114 antibody, GCSFR antibody, Cd114 antibody, Csfgr antibody, G-CSF-R antibody, G-CSFR antibody, CSF3R antibody, gcsfr antibody, cd114 antibody, colony stimulating factor 3 receptor antibody, colony stimulating factor 3 receptor (granulocyte) antibody, colony stimulating factor 3 receptor L homeolog antibody, granulocyte colony-stimulating factor receptor antibody, CSF3R antibody, Csf3r antibody, csf3r antibody, csf3r.L antibody, LOC100433338 antibody
    背景
    CSF3R(Colony-Stimulating Factor 3 Receptor, Granulocyte) also known as GCSFR or CD114((Cluster of Differentiation 114) is a protein that in humans is encoded by the CSF3R gene. G-CSF-R is a cell-surface receptor for the granulocyte colony-stimulating factor(G-CSF). The G-CSF receptors belongs to a family of cytokine receptors known as the hematopoietin receptor family. The CSF3R gene consists of 17 exons. By in situ hybridization using human CSF3R cDNA as a probe, Inazawa et al.(1991) localized the gene to 1p35-p34.3. The G-CSF-R is a transmembrane receptor that consists of an extracellular ligand-binding portion, a transmembrane domain, and the cytoplasmic portion that is responsible for signal transduction. GCSF-R ligand-binding is associated with dimerization of the receptor and signal transduction through proteins including Jak, Lyn, STAT, and Erk1/2. Dong et al.(2001) reported that the C terminus of CSF3R is required for SHP1 downregulation of CSF3-induced STAT activation. The authors proposed that this mechanism inhibits cell proliferation and survival in response to CSF3.

    Synonyms: CD 114 antibody|CD114 antibody|CD114 antigen antibody|Colony stimulating factor 3 receptor(granulocyte) antibody|Colony stimulating factor 3 receptor antibody|CSF 3R antibody|CSF3R antibody|CSF3R_HUMAN antibody|Csfgr antibody|G CSF R antibody|G-CSF receptor antibody|G-CSF-R antibody|GCSFR antibody|Granulocyte colony stimulating factor receptor antibody|Granulocyte colony stimulating factor receptor precursor antibody|Granulocyte colony-stimulating factor receptor antibody|OTTHUMP00000009703 antibody|OTTHUMP00000009704 antibody|OTTHUMP00000009705 antibody
    UniProt
    Q99062
You are here:
客服