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CSF3R 抗体

CSF3R 适用: 人 FACS 宿主: 小鼠 Monoclonal LMM741 unconjugated
产品编号 ABIN2869977
发货至: 中国
  • 抗原 See all CSF3R 抗体
    CSF3R (Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R))
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CSF3R antibody is un-conjugated
    应用范围
    • 62
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    Flow Cytometry (FACS)
    特异性
    The mouse monoclonal antibody LMM741 recognizes an extracellular epitope of CD114 (colony stimulating factor 3 receptor), a 130 kDa transmembrane glycoprotein expressed on granulocytes and their differentiation stages, on monocytes, platelets, endothelial cells and placenta. It is absent from lymphocytes and erythrocytes.
    无交叉反应
    小鼠
    交叉反应 (详细)
    Human
    纯化方法
    Purified by protein-A affinity chromatography.
    纯度
    > 95 % (by SDS-PAGE)
    免疫原
    CHO cells transfected with human CD114
    克隆位点
    LMM741
    亚型
    IgG1 kappa
    Top Product
    Discover our top product CSF3R Primary Antibody
  • 应用备注
    Flow cytometry: Recommended dilution: 1-4 μg/mL.
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Do not freeze.
  • 抗原
    CSF3R (Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R))
    别名
    CD114 / G-CSFR (CSF3R 产品)
    别名
    CD114 antibody, GCSFR antibody, Cd114 antibody, Csfgr antibody, G-CSF-R antibody, G-CSFR antibody, CSF3R antibody, gcsfr antibody, cd114 antibody, colony stimulating factor 3 receptor antibody, colony stimulating factor 3 receptor (granulocyte) antibody, colony stimulating factor 3 receptor L homeolog antibody, granulocyte colony-stimulating factor receptor antibody, CSF3R antibody, Csf3r antibody, csf3r antibody, csf3r.L antibody, LOC100433338 antibody
    背景
    Colony stimulating factor 3 receptor,CD114 / G-CSFR (granulocyte colony-stimulating factor receptor, also known as CSF3R) is a type I transmembrane glycoprotein which upon binding of its ligand (G-CSF, granulocyte colony-stimulating factor) homodimerizes and activates signaling transduction to mediate cell proliferation, survival, and differentiation. It is expressed by granulocytes at all stages of their differentiation, as well as by monocytes, dendritic cells, and mature platelets. Among non-hematopoietic cells, it is expressed e.g. by endothelial cells, placenta, trophoblasts, and many tumor cell lines. This antigen is a target for stem cell mobilization for blood stem cell transplantation, for enhancing recovery of myelopoiesis following chemotherapy and in the treatment of patients with severe chronic neutropenia.,GCSFR, CSF3R, SCN7
    基因ID
    1441
    UniProt
    Q99062
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