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LTBR 抗体 (C-Term)

LTBR 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3044034
发货至: 中国
  • 抗原 See all LTBR 抗体
    LTBR (Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR))
    抗原表位
    • 15
    • 9
    • 7
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 420-435, C-Term
    适用
    • 54
    • 50
    • 1
    宿主
    • 47
    • 17
    • 16
    克隆类型
    • 49
    • 29
    多克隆
    标记
    • 46
    • 7
    • 6
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LTBR antibody is un-conjugated
    应用范围
    • 53
    • 34
    • 23
    • 13
    • 13
    • 10
    • 9
    • 7
    • 7
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for Tumor necrosis factor receptor superfamily member 3(LTBR) detection. Tested with WB, IHC-P in Human.
    序列
    ATPSNRGPRN QFITHD
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Tumor necrosis factor receptor superfamily member 3(LTBR) detection. Tested with WB, IHC-P in Human.
    Gene Name: lymphotoxin beta receptor(TNFR superfamily, member 3)
    Protein Name: Tumor necrosis factor receptor superfamily member 3
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the C-terminus of human LTBR(420-435aa ATPSNRGPRNQFITHD).
    亚型
    IgG
    Top Product
    Discover our top product LTBR Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for LTBR is approximately 2.5 ng/lane under reducing conditions.
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    有效期
    12 months
  • 抗原
    LTBR (Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR))
    别名
    LTBR (LTBR 产品)
    别名
    AI256028 antibody, CD18 antibody, LTbetaR antibody, Ltar antibody, TNF-R-III antibody, TNFCR antibody, TNFR-RP antibody, TNFR2-RP antibody, TNFRrp antibody, Tnfbr antibody, Tnfrsf3 antibody, D12S370 antibody, LT-BETA-R antibody, TNFR3 antibody, TNFRSF3 antibody, lymphotoxin beta receptor antibody, lymphotoxin B receptor antibody, Ltbr antibody, LTBR antibody
    背景
    LTBR(Lymphotoxin B Receptor), also called TNFCR or LT-BETA-R, is a receptor for lymphotoxin which in humans is encoded by the LTBR gene. By linkage analysis with recombinant inbred mouse strains, Nakamura et al.(1995) demonstrated that the Tnfcr locus is close to the Tnfr1 gene on mouse chromosome 6. Presumably, the human homolog is located on 12p13. Silva-Santos et al.(2005) reported that double-positive T cells regulate the differentiation of early thymocyte progenitors and gamma-delta cells by a mechanism dependent on the transcription factor ROR-gamma-t and the lymphotoxin-beta receptor. Lo et al.(2007) identified lymphotoxin and LIGHT(TNFSF14), tumor necrosis factor cytokine family members that are primarily expressed on lymphocytes, as critical regulators of key enzymes that control lipid metabolism.

    Synonyms: CD 18 antibody|CD18 antibody|CD18 antigen antibody|D12S370 antibody|LT beta R antibody|LTBETAR antibody|Ltbr antibody|Lymphotoxin B receptor antibody|Lymphotoxin beta receptor(TNFR superfamily, member 3) antibody|Lymphotoxin beta receptor antibody|Lymphotoxin-beta receptor antibody|TNF R III antibody|TNF-RIII antibody|TNFCR antibody|TNFR RP antibody|TNFR superfamily member 3 antibody|TNFR-III antibody|TNFR2 RP antibody|TNFR2RP antibody|TNFR3 antibody|TNFRII antibody|TNFRRP antibody|TNFRSF 3 antibody|TNFRSF3 antibody|TNR3_HUMAN antibody|Tumor necrosis factor C receptor antibody|Tumor necrosis factor receptor 2 related protein antibody|Tumor necrosis factor receptor 2-related protein antibody|Tumor necrosis factor receptor superfamily member 3 antibody|Tumor necrosis factor receptor superfamily member 3 precursor antibody|Tumor necrosis factor receptor type III antibody
    UniProt
    P36941
    途径
    NF-kappaB Signaling
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