CASP14 抗体 (C-Term)
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- 抗原 See all CASP14 抗体
- CASP14 (Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14))
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抗原表位
- AA 223-242, C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CASP14 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for Inactive Caspase-14(CASP14) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
- 序列
- KARKTNPEIQ STLRKRLYLQ
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Inactive Caspase-14(CASP14) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: caspase 14, apoptosis-related cysteine peptidase
Protein Name: Caspase-14 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human Caspase-14(223-242aa KARKTNPEIQSTLRKRLYLQ), different from the related rat and mouse sequences by four amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product CASP14 Primary Antibody
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anti-Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14) (AA 133-242) antibody
CASP14 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4C9 unconjugated
anti-Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14) antibodyCASP14 适用: 人, 小鼠, 大鼠, 犬, Gerbil WB, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14) (AA 223-242) antibodyCASP14 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14) (C-Term) antibodyCASP14 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14) (AA 17-248) antibodyCASP14 适用: 小鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14) (AA 1-242) antibodyCASP14 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14) (AA 171-230) antibodyCASP14 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14) antibodyCASP14 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14) (AA 1-246) antibodyCASP14 适用: 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14) (AA 155-242) antibodyCASP14 适用: 人, 小鼠, 大鼠 ELISA, ICC, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat, The detection limit for CASP14 is approximately 0.5 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Thimerosal (Merthiolate), Sodium azide
- 注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - 有效期
- 12 months
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- 抗原
- CASP14 (Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14))
- 别名
- CASP14 (CASP14 产品)
- 别名
- CASP14 antibody, MICE antibody, mini-ICE antibody, caspase 14, apoptosis-related cysteine peptidase antibody, caspase 14 antibody, caspase-14-like antibody, caspase-14 antibody, CASP14 antibody, Casp14 antibody, LOC485601 antibody, LOC780455 antibody
- 背景
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Caspase 14 is an enzyme that in humans is encoded by the CASP14 gene. CASP14 belongs the evolutionarily conserved caspase family. CASP14 was assigned to chromosome 19p13.1. Using Northern blot and semiquantitative RT-PCR analyses, it was showed that CASP14 was transcriptionally upregulated during maintenance of confluent cultures of human epidermal keratinocytes. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier. Caspase 14 seems to play a role in keratinocyte differentiation and cornification and probably regulates maturation of the epidermis by proteolytically processing filaggrin.
Synonyms: Apoptosis related cysteine protease antibody|CASP 14 antibody|CASP-14 antibody|CASP14 antibody|Caspase 14 apoptosis related cysteine protease antibody|Caspase 14 precursor antibody|Caspase-14 subunit p10 antibody|Caspase14 antibody|CASPE_HUMAN antibody|MGC119078 antibody|MGC119079 antibody|MICE antibody|Mini ICE antibody - UniProt
- P31944
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