ITPR3 抗体 (N-Term)
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- 抗原 See all ITPR3 抗体
- ITPR3 (Inositol 1,4,5-Trisphosphate Receptor, Type 3 (ITPR3))
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抗原表位
- AA 70-95, N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ITPR3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for Inositol 1,4,5-trisphosphate receptor type 3(ITPR3) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
- 序列
- QYWKAKQTKQ DKEKIADVVL LQKLQH
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Inositol 1,4,5-trisphosphate receptor type 3(ITPR3) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: inositol 1,4,5-trisphosphate receptor, type 3
Protein Name: Inositol 1,4,5-trisphosphate receptor type 3 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human ITPR3 (70-95aa QYWKAKQTKQDKEKIADVVLLQKLQH), identical to the related mouse and rat sequences.
- 亚型
- IgG
- Top Product
- Discover our top product ITPR3 Primary Antibody
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anti-Inositol 1,4,5-Trisphosphate Receptor, Type 3 (ITPR3) (AA 2411-2758) antibody
ITPR3 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Inositol 1,4,5-Trisphosphate Receptor, Type 3 (ITPR3) antibodyITPR3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Inositol 1,4,5-Trisphosphate Receptor, Type 3 (ITPR3) (AA 1630-1870) antibodyITPR3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Inositol 1,4,5-Trisphosphate Receptor, Type 3 (ITPR3) antibodyITPR3 适用: 人, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Inositol 1,4,5-Trisphosphate Receptor, Type 3 (ITPR3) (AA 625-675) antibodyITPR3 适用: 人 IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for ITPR3 is approximately 0.1 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- ITPR3 (Inositol 1,4,5-Trisphosphate Receptor, Type 3 (ITPR3))
- 别名
- ITPR3 (ITPR3 产品)
- 别名
- Ip3r3 antibody, Itpr-3 antibody, IP3R antibody, IP3R3 antibody, IP3R3X antibody, inositol 1,4,5-triphosphate receptor 3 antibody, inositol 1,4,5-trisphosphate receptor type 3 antibody, inositol 1,4,5-trisphosphate receptor, type 3 antibody, Itpr3 antibody, ITPR3 antibody
- 背景
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ITPR3 encodes a receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. The receptor contains a calcium channel at the C-terminus and the ligand-binding site at the N-terminus. Knockout studies in mice suggest that type 2 and type 3 inositol 1,4,5-trisphosphate receptors play a key role in exocrine secretion underlying energy metabolism and growth. ITP3 channels serve an important role in the taste transduction pathway of sweet, bitter and umami tastes the gustatory system. ITP3 channels allow the flow of Calcium out of the endoplasmic reticulum in response to IP3. Calcium cations result in the activation of TRPM5 which leads to a depolarisation generating potential and an action potential.
Synonyms: 4 antibody|5-trisphosphate receptor antibody|5-trisphosphate receptor type 3 antibody| FLJ36205 antibody|Inositol 1 antibody|Inositol 1,4,5 trisphosphate receptor type 3 antibody|InsP3R3 antibody|IP3 receptor antibody|IP3 receptor isoform 3 antibody|IP3R 3 antibody|IP3R antibody|IP3R3 antibody|ITPR 3 antibody|ITPR3 antibody|ITPR3_HUMAN antibody| Type 3 inositol 1 antibody|Type 3 inositol 1,4,5 trisphosphate receptor antibody|Type 3 InsP3 receptor antibody - 基因ID
- 3710
- UniProt
- Q14573
- 途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, BCR Signaling
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