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ITPR3 抗体 (AA 2411-2758)

ITPR3 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3031328
发货至: 中国
  • 抗原 See all ITPR3 抗体
    ITPR3 (Inositol 1,4,5-Trisphosphate Receptor, Type 3 (ITPR3))
    抗原表位
    • 15
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2411-2758
    适用
    • 20
    • 19
    • 4
    • 1
    人, 小鼠, 大鼠
    宿主
    • 32
    • 1
    克隆类型
    • 34
    多克隆
    标记
    • 13
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ITPR3 antibody is un-conjugated
    应用范围
    • 20
    • 14
    • 13
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    Antigen affinity
    免疫原
    Human partial recombinant protein (AA 2411-2758) was used as the immunogen for this IP3R antibody.
    亚型
    IgG
  • 应用备注
    The stated application concentrations are suggested starting amounts. Titration of the IP3R antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the IP3R antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    ITPR3 (Inositol 1,4,5-Trisphosphate Receptor, Type 3 (ITPR3))
    别名
    IP3R (ITPR3 产品)
    别名
    Ip3r3 antibody, Itpr-3 antibody, IP3R antibody, IP3R3 antibody, IP3R3X antibody, inositol 1,4,5-triphosphate receptor 3 antibody, inositol 1,4,5-trisphosphate receptor type 3 antibody, inositol 1,4,5-trisphosphate receptor, type 3 antibody, Itpr3 antibody, ITPR3 antibody
    背景
    Inositol 1,4,5-trisphosphate receptor type 1, also known as IP3R or IP3R1, is a protein that in humans is encoded by the ITPR1 gene. It is mapped to 3p26.1. The product of the ITPR1 gene is predominantly enriched in cerebellar Purkinje cells but is also concentrated in neurons in the hippocampal CA1 region, caudate-putamen, and cerebral cortex. IP3R is an intracellular IP3-gated calcium channel that modulates intracellular calcium signaling. Upon stimulation by inositol 1,4,5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in the gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders.
    基因ID
    3708
    途径
    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, BCR Signaling
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