RAD51 抗体 (AA 1-258)
Quick Overview for RAD51 抗体 (AA 1-258) (ABIN3043560)
抗原
See all RAD51 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-258
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原理
- Anti-Rad51 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Rad51 Antibody Picoband® (ABIN3043560). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Rad51 recombinant protein (Position: M1-E258). Human Rad51 shares 98% amino acid (aa) sequence identity with mouse Rad51.
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亚型
- IgG
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anti-DNA Repair Protein Homolog 1 (RAD51) (AA 1-339) antibody
RAD51 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-DNA Repair Protein Homolog 1 (RAD51) (Center) antibodyRAD51 适用: 人, 小鼠 WB, IP, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-DNA Repair Protein Homolog 1 (RAD51) (AA 81-180) antibodyRAD51 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-DNA Repair Protein Homolog 1 (RAD51) (AA 1-228) antibodyRAD51 适用: 人 WB, ELISA, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-DNA Repair Protein Homolog 1 (RAD51) (AA 1-339) antibodyRAD51 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-DNA Repair Protein Homolog 1 (RAD51) (AA 1-242) antibodyRAD51 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E5-E5 unconjugated
anti-DNA Repair Protein Homolog 1 (RAD51) (AA 1-134) antibodyRAD51 适用: 人 IHC, FACS, ISt, StM 宿主: 小鼠 Monoclonal RAD51-2702 unconjugated
anti-DNA Repair Protein Homolog 1 (RAD51) (AA 1-134) antibodyRAD51 适用: 人 WB, IHC, FACS, ISt, StM 宿主: 小鼠 Monoclonal RAD51-2701 unconjugated
anti-DNA Repair Protein Homolog 1 (RAD51) (AA 1-242) antibodyRAD51 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 4C11-B4 unconjugated
anti-DNA Repair Protein Homolog 1 (RAD51) antibodyRAD51 适用: 人, 小鼠 WB, ELISA, IP, IF 宿主: 小鸡 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. Kato, M., Yano, K., Matsuo, F., Saito, H., Katagiri, T., Kurumizaka, H., Yoshimoto, M., Kasumi, F., Akiyama, F., Sakamoto, G., Nagawa, H., Nakamura, Y., Miki, Y. : Identification of Rad51 alteration in patients with bilateral breast cancer. J. Hum. Genet. 45: 133-137, 2000. 2. Daniel DC (2002). "Highlight: BRCA1 and BRCA2 proteins in breast cancer.". Microsc. Res. Tech. 59 (1): 68-83. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- RAD51 (DNA Repair Protein Homolog 1 (RAD51))
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别名
- RAD51
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背景
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Synonyms: DNA repair protein RAD51 homolog 1,HsRAD51,hRAD51,RAD51 homolog A,RAD51,RAD51A, RECA,
Tissue Specificity: Highly expressed in testis and thymus, followed by small intestine, placenta, colon, pancreas and ovary. Weakly expressed in breast.
Background: DNA repair protein RAD51 homolog 1, also known as RAD51A, is a human gene. The Rad51 gene, HsRAD51, is a homolog of RecA of Escherichia coli and functions in recombination and DNA repair. BRCA1 and BRCA2 proteins form a complex with Rad51, and these genes are thought to participate in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. RAD51 is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis.
Sequence Similarities: Belongs to the RecA family. RAD51 subfamily.
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分子量
- 37 kDa
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基因ID
- 5888
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UniProt
- Q06609
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途径
- DNA Damage Repair
抗原
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