(27 references)-
- 抗原 See all COL3A1 抗体
- COL3A1 (Collagen, Type III, alpha 1 (COL3A1))
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抗原表位
- AA 1200-1221, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This COL3A1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 原理
- Rabbit IgG polyclonal antibody for Collagen alpha-1(III) chain(COL3A1) detection. Tested with WB in Human.
- 序列
- VGAAAIAGIG GEKAGGFAPY YG
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Collagen alpha-1(III) chain(COL3A1) detection. Tested with WB in Human.
Gene Name: collagen, type III, alpha 1
Protein Name: Collagen alpha-1(III) chain - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human Collagen III(1200-1221aa VGAAAIAGIGGEKAGGFAPYYG), different from the related mouse sequence by four amino acids, and from the related rat sequence by five amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product COL3A1 Primary Antibody
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anti-Collagen, Type III, alpha 1 (COL3A1) (C-Term) antibody
COL3A1 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Collagen, Type III, alpha 1 (COL3A1) (AA 1217-1466) antibodyCOL3A1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Collagen, Type III, alpha 1 (COL3A1) (AA 24-153) antibodyCOL3A1 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 8C1G11 unconjugated
anti-Collagen, Type III, alpha 1 (COL3A1) (AA 1171-1435) antibodyCOL3A1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Collagen, Type III, alpha 1 (COL3A1) (AA 1059-1466) antibodyCOL3A1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Collagen, Type III, alpha 1 (COL3A1) antibodyCOL3A1 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Collagen, Type III, alpha 1 (COL3A1) antibodyCOL3A1 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p) 宿主: 小鼠 Monoclonal 5G2 unconjugated
anti-Collagen, Type III, alpha 1 (COL3A1) (N-Term) antibodyCOL3A1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Collagen, Type III, alpha 1 (COL3A1) (AA 1171-1435) antibodyCOL3A1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C10 unconjugated
anti-Collagen, Type III, alpha 1 (COL3A1) (N-Term) antibodyCOL3A1 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig, 兔 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for Collagen III is approximately 0.25 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Thimerosal (Merthiolate), Sodium azide
- 注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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: "BMP‑7 suppresses excessive scar formation by activating the BMP‑7/Smad1/5/8 signaling pathway." in: Molecular medicine reports, Vol. 16, Issue 2, pp. 1957-1963, (2018) (PubMed).
: "Hydrogen sulfide attenuates myocardial fibrosis in diabetic rats through the JAK/STAT signaling pathway." in: International journal of molecular medicine, Vol. 41, Issue 4, pp. 1867-1876, (2018) (PubMed).
: "In vitro differentiation of endometrial regenerative cells into smooth muscle cells: Α potential approach for the management of pelvic organ prolapse." in: International journal of molecular medicine, Vol. 38, Issue 1, pp. 95-104, (2017) (PubMed).
: "Erratum: Long-term intravenous administration of carboxylated single-walled carbon nanotubes induces persistent accumulation in the lungs and pulmonary fibrosis via the nuclear factor-kappa B pathway ..." in: International journal of nanomedicine, Vol. 12, pp. 1515, (2017) (PubMed).
: "Continuing treatment with Salvia miltiorrhiza injection attenuates myocardial fibrosis in chronic iron-overloaded mice." in: PLoS ONE, Vol. 10, Issue 4, pp. e0124061, (2016) (PubMed).
: "Effects of rhBNP on myocardial fibrosis after myocardial infarction in rats." in: International journal of clinical and experimental pathology, Vol. 8, Issue 6, pp. 6407-15, (2016) (PubMed).
: "Silica promotes the transdifferentiation of rat circulating fibrocytes in vitro." in: Molecular medicine reports, Vol. 12, Issue 4, pp. 5828-36, (2016) (PubMed).
: "Astragalus membranaceus ameliorates renal interstitial fibrosis by inhibiting tubular epithelial-mesenchymal transition in vivo and in vitro." in: Experimental and therapeutic medicine, Vol. 11, Issue 5, pp. 1611-1616, (2016) (PubMed).
: "Role of rat autologous skin fibroblasts and mechanism underlying the repair of depressed scars." in: Experimental and therapeutic medicine, Vol. 12, Issue 2, pp. 945-950, (2016) (PubMed).
: "CYP epoxygenase 2J2 prevents cardiac fibrosis by suppression of transmission of pro-inflammation from cardiomyocytes to macrophages." in: Prostaglandins & other lipid mediators, Vol. 116-117, pp. 64-75, (2015) (PubMed).
: "Antiphotoaging effect of conditioned medium of dedifferentiated adipocytes on skin in vivo and in vitro: a mechanistic study." in: Stem cells and development, Vol. 24, Issue 9, pp. 1096-111, (2015) (PubMed).
: "Mechanisms of nerve capping technique in prevention of painful neuroma formation." in: PLoS ONE, Vol. 9, Issue 4, pp. e93973, (2015) (PubMed).
: "Over-expression of calpastatin inhibits calpain activation and attenuates post-infarction myocardial remodeling." in: PLoS ONE, Vol. 10, Issue 3, pp. e0120178, (2015) (PubMed).
: "Uighur medicine abnormal savda munzip (ASMq) suppresses expression of collagen and TGF-β1 with concomitant induce Smad7 in human hypertrophic scar fibroblasts." in: International journal of clinical and experimental medicine, Vol. 8, Issue 6, pp. 8551-60, (2015) (PubMed).
: "Association between pelvic organ prolapse and stress urinary incontinence with collagen." in: Experimental and therapeutic medicine, Vol. 7, Issue 5, pp. 1337-1341, (2014) (PubMed).
: "?-catenin is overexpressed in hepatic fibrosis and blockage of Wnt/?-catenin signaling inhibits hepatic stellate cell activation." in: Molecular medicine reports, Vol. 9, Issue 6, pp. 2145-51, (2014) (PubMed).
: "Localization of human mesenchymal stem cells from umbilical cord blood and their role in repair of diabetic foot ulcers in rats." in: International journal of biological sciences, Vol. 10, Issue 1, pp. 80-9, (2014) (PubMed).
: "Multitargeted inhibition of hepatic fibrosis in chronic iron-overloaded mice by Salvia miltiorrhiza." in: Journal of ethnopharmacology, Vol. 148, Issue 2, pp. 671-81, (2013) (PubMed).
: "Effect of farnesyltransferase inhibition on cardiac remodeling in spontaneously hypertensive rats." in: International journal of cardiology, Vol. 168, Issue 4, pp. 3340-7, (2013) (PubMed).
: "Anti-fibrotic effects of puerarin on CCl4-induced hepatic fibrosis in rats possibly through the regulation of PPAR-? expression and inhibition of PI3K/Akt pathway." in: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, Vol. 56, pp. 436-42, (2013) (PubMed).
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: "BMP‑7 suppresses excessive scar formation by activating the BMP‑7/Smad1/5/8 signaling pathway." in: Molecular medicine reports, Vol. 16, Issue 2, pp. 1957-1963, (2018) (PubMed).
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- 抗原
- COL3A1 (Collagen, Type III, alpha 1 (COL3A1))
- 别名
- COL3A1 (COL3A1 产品)
- 别名
- EDS4A antibody, AW550625 antibody, Col3a-1 antibody, MMS10-W antibody, Ms10w antibody, mKIAA4231 antibody, col3a1 antibody, collagen type III alpha 1 chain antibody, collagen, type III, alpha 1 antibody, collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant) S homeolog antibody, COL3A1 antibody, Col3a1 antibody, col3a1 antibody, col3a1.S antibody
- 背景
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COL3A1, also called EDS4A or Collagen alpha-1(III), is a protein that in humans is encoded by the COL3A1 gene, it is mapped to 2q32.2. COL3A1 chain is a fibrillar-forming collagen comprising 3 alpha-1(III) chains and is expressed in early embryos and throughout embryogenesis. In adult, COL3A1 is a major component of the extracellular matrix in a variety of internal organs and skin. COL3A1 is also a fibrous scleroprotein in bone, cartilage, dentin, tendon, bone marrow stroma and other connective tissue. It is involved in regulation of cortical development, and it Is the major ligand of GPR56 in the developing brain.COL3A1 binding to GPR56 can inhibit neuronal migration and activate the RhoA pathway by coupling GPR56 to GNA13 and possibly GNA12
Synonyms: CO3A1_HUMAN antibody|COL 3A1 antibody|COL3A1 antibody|Collagen alpha 1(III) chain antibody|Collagen alpha-1(III) chain antibody|Collagen III alpha 1 chain precursor antibody|Collagen III alpha 1 polypeptide antibody|Collagen type III alpha 1 (Ehlers Danlos syndrome type IV autosomal dominant) antibody|Collagen type III alpha 1 antibody|Collagen type III alpha antibody|EDS4A antibody|Ehlers Danlos syndrome type IV, autosomal dominant antibody|Fetal collagen antibody|Type III collagen antibody - 基因ID
- 1281
- UniProt
- P02461
- 途径
- Autophagy, Growth Factor Binding
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